XB-FEAT-492558

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sh3kbp1

This is the community wiki page for the gene sh3kbp1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenlcature changes/notes

Also known as HSB1; AGMX2; CIN85; GIG10; HSB-1; IMD61; MIG18; CD2BP3

Summary from NCBI for human SH3KBP1

This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]