XB-FEAT-995375

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c1r

This is the community wiki page for the gene c1r please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

02.25.20 name changed from 'complement component 1, r subcomponent' to 'complement C1r', following Human nomenclature.

Summary fro human CR1 from NCBI

This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]