XB-FEAT-963445

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atp5mf

This is the community wiki page for the gene atp5mf please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

12.04.2017

Human symbol has changed for genepage ID: 963445 From atp5j2 to atp5mf

undated change

Human name changed for Gene ID: 9551 from ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 to ATP synthase membrane subunit f

Summary from NCBI

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene. [provided by RefSeq, Nov 2010]