Forskolin

From Xenbase
Jump to: navigation, search

Description

Activator of adenylyl cyclase.

Marketed as a dietary supplement/alternative medication.

"Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase."

    • -Sigma product description
forskolin structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

50uM

References

>786 Xenbase articles contain a reference to Forskolin according to textpresso