XB-FEAT-494949

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rac2

This is the community wiki page for the gene rac2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

08/15/2017

Human name has changed for Entrez Gene: 5880. From ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) to Rac family small GTPase 2

summary from NCBI

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]