XB-FEAT-945276

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cavin2

This is the community wiki page for the gene cavin2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


nomenclature changes

undated

Symbol changed from sdpr to cavin2

Name changed from serum deprivation-response protein to caveolae associated protein 2

summary from NCBI

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]