XB-FEAT-1017181

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wasl

This is the community wiki page for the gene wasl please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

04/22/ 2016

Human name has changed for Entrez Gene: 8976. From Wiskott-Aldrich syndrome-like to Wiskott-Aldrich syndrome like.

05.13.19

Human name has changed for Entrez Gene: 8976. From Wiskott-Aldrich syndrome like to WASP like actin nucleation promoting factor

Summary from NCBI for human WASL

This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]