XB-FEAT-5758396

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igkv3-20l1

This is the community wiki page for the gene igkv3-20l1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

7Sept2022

Name gene name and symbol changed from XB5758396 to igkv3-20l1 immunoglobulin kappa variable 3-20 like 1.

This gene was named following alignement of the X. tropicalis and X. laevis proteins to precalculated orthology groups in the DIOPT program, EggNogg. It aligned to 900+ other proteins from 68 species (including to other Xenopus tropicalis proteins) in the IGKV family. As the human genes which are named igkv3-20– immunoglobulin kappa variable 3-20, we have provisonally adopted this name. As there is some variability in subfamilies, I have provisionally added the like suffix, and as several genes exist, I've given them=m serial numbers, this gene being 1.

summary for human IGKV3-20 from AGR and NCBI

Involved in antibacterial humoral response and glomerular filtration. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Apr 2022]