XB-FEAT-5759091

prph2l

This is the community wiki page for the gene prph2l please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

This gene was often called PRPH2LA, but based on orthology/synteny it is shown to be lost in placental mammals.

02.03.2021 Following orthology/synteny assessment by David Webb (NCBI- REF Seq) See RSCOM-111: [1]

gene name changed from photoreceptor outer segment membrane glycoprotein 2-like to peripherin 2 like

gene symbol changed from XB5759091 to prph2l

synteny notes

Note, all gnathostomes have PRPH2>...<UBR2 which parallel "PRPH2L">...<UBR1

non-placental gnathostomes STARD9>...CDAN1<...loc>...TTBK2<..."PRPH2L">...UBR1<...TMEM62>...PTGR2<

• General synteny with some taxon-specific re-arrangement. LOC between CDAN1 and TTBK2 comes and goes. Synteny in fish often reduced to "PRPH2L">...UBR1<.

monotremes STARD9>...CDAN1<...TTBK2<...LOC>...UBR1<

• LOC probably not a PRPH2-like pseudogene

marsupials STARD9>...CDAN1<....TTBK2<..."PRPH2L">...UBR1<...TMEM62>

placental mammals (lost) STARD9>...CDAN1<....TTBK2<...FDPSP4<...UBR1<...TMEM62>

• I couldn't find a PRPH2-like pseudogene between TTBK2 and URB1 in placental mammals. Instead, many species had an unrelated FDPSP4 pseudogene between those genes.