XB-FEAT-5787648

mpp1

This is the community wiki page for the gene mpp1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

01/12/2016

Human name has changed for Entrez Gene: 4354. From membrane protein, palmitoylated 1, 55kDa to membrane protein, palmitoylated 1

10.20.2021

Human name has changed for Entrez Gene: 4354 (MPP1). From membrane palmitoylated protein 1 to MAGUK p55 scaffold protein 1

summary for human MPP1 from NCBI

Also known as: MRG1; PEMP; AAG12; EMP55; DXS552E

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]