XB-FEAT-5914982

ripkl3.2

This is the community wiki page for the gene ripk3l.2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature updates

12.31.2019

This gene was renamed after a review by David Webb from the NCBI and Xenbase curators. It was changed from ripk3 gene 2 one to a ripk3-like gene 2 after a synteny analysis.

In Xenopus, the true ripk3 genes occur in a conserved order, in humans, frog, lizard and turtles, as nfatc4> ripk3> adcy4>, and is on Chromosome 1.

In Xenopus the ripk3-like gene 2 genes are currently placed on Chr8, although this needs more study to determine for sure. ( watch this space!)

It seems that the ripk3l.1 and ripk3l.2 genes do not occur in any other vertebrates except the caecillian (Rhinatrema bivittatum), and may represent an amphibian-specific gene duplication event.