XB-FEAT-6372191

prss3

This is the community wiki page for the gene prss3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

01/12/2016 Human name has changed for Entrez Gene: 5646. From protease, serine, 3 to protease, serine 3

01/22/2018 Human name has changed for Entrez Gene: 5646. From protease, serine 3 to serine protease 3

Summary from NCBI

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]

Expression

in adult humans, expression restricted to pancreas