BAPTA-AM: Difference between revisions
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imported>Kevin (Created page with "==Description== Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1...") |
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==Description== | ==Description== | ||
Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro. | Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro. | ||
[[File:BAPTAAM.png]] | [[File:BAPTAAM.png|frame|right|Structure of BAPTA-AM, photo from Sigma-Aldrich]] | ||
**Genes Affected | **Genes Affected | ||
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==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/2293 PubChem] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=4661 Leclerc et al., 2003] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=4661 Leclerc et al., 2003] | ||
>762 Xenbase articles contain a reference to BAPTA-AM according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | >762 Xenbase articles contain a reference to BAPTA-AM according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | |||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | |||
Latest revision as of 13:28, 2 June 2015
Description
Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.
Suppliers
Usage Notes
.4uM in .1x NAM
References
>762 Xenbase articles contain a reference to BAPTA-AM according to textpresso