Barasertib

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Description

Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis.

Barasertib structure, image from PubChem

Alternative names

  • AZD1152
  • UNII-16XC2U7W8N

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Usage Notes

References

> 7 Xenbase articles contain a reference to Barasertib or AZD1152 according to textpresso