Cyclosporin A: Difference between revisions
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Synonym CsA | ==Synonym== | ||
CsA | |||
[[File:cyclosporinA.png|frame|right|Cyclosporin A structure, photo from Pubchem]] | [[File:cyclosporinA.png|frame|right|Cyclosporin A structure, photo from Pubchem]] | ||
Revision as of 07:16, 17 September 2018
Description
"Cyclic oligopeptide with immunosuppressant properties. Induces apoptosis in rat thymocytes and in the murine B cell lymphoma cell line, WEH1-231. However, prevents anti-IgM and ionomycin-induced apoptosis in BLB cell lines. The complex of cyclosporin A with cyclophilin inhibits protein phosphatase 2B with nanomolar affinity. Inhibits nitric oxide synthesis induced by interleukin-1α, lipopolysaccharides, and TNF-α. Induces cardiomyocytes from embryonic stem cells."
- -Calbiochem Product Description
Synonym
CsA
![](/xenwiki/images/c/c6/CyclosporinA.png)
Genes Affected
Suppliers
Usage Notes
References
>161 Xenbase articles contain a reference to Cyclosporin A according to textpresso