Lovastatin

Description

"Lovastatin is a fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver." Source: MeSH

structure, image from PubChem

Alternative names

• 75330-75-5
• mevinolin
• Mevacor
• Lovalip

References

• Cerqueira et al 2014
• NCBI PubChem CID:53232

> 65 Xenbase articles contain a reference to Lovastatin or Mevinolin according to textpresso

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