NH-3

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Description

NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment.

formula

C28H27NO6

Synonyms

thyromimetic, 5b

Suppliers

Usage Notes

References

PubMed ID: 37083105 https://pubmed.ncbi.nlm.nih.gov/37083105/