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Synonym: Mifepristone "Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME."

  • -Pubchem Description
RU486 structure, photo from pubchem

Genes Affected


Usage Notes


>43 Xenbase articles contain a reference to RU486 according to textpresso