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Synonym Rap "Rapamycin is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties."

  • -Pubchem Description
rapamycin structure, photo from PubChem

Genes Affected


Usage Notes


>172 Xenbase articles contain a reference to rapamycin according to textpresso