Small Molecules for Xenopus Research: Difference between revisions

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==Notice to our users==
Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.
==Important small molecule references==
==Important small molecule references==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem]
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*[[Chelerythrine]]
*[[Chelerythrine]]
*[[chymostatin ]]
*[[chymostatin ]]
*[[Colcemide]]
*[[concanamycin]]
*[[concanamycin]]
*[[cycloheximide]]
*[[cycloheximide]]
*[[cyclopamine]]
*[[cyclopamine]]
*[[Cyclosporin A]]
*[[Cytochalasin B]]
*[[Cytochalasin B]]
*[[cytochalasin D]]
*[[Colcemide|Demecolcine]]
*[[deltamethrin]]
*[[dexamethosone]]
*[[dexamethosone]]
*[[DHT(dihydrotestosterone)]]
*[[DHT(dihydrotestosterone)]]
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*[[herbimycin A]]
*[[herbimycin A]]
*[[IBMX]]
*[[IBMX]]
*[[jasplakinolide]]
*[[KT 5720]]
*[[KT 5720]]
*[[lansoprazole]]
*[[lansoprazole]]
*[[LiCl]]
*[[LiCl]]
*[[Mg132]]
*[[Mg132]]
*[[mHip]]
*[[MMP-2 inhibitor II]]
*[[MMP-2 inhibitor II]]
*[[nicorandil]]
*[[nicorandil]]
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*[[NSC-87877]]
*[[NSC-87877]]
*[[o-phenanthroline]]
*[[o-phenanthroline]]
*[[okadaic acid]]
*[[olomoucine]]
*[[olomoucine]]
*[[ouabain]]
*[[ouabain]]
*[[p-MPPI]]
*[[p-MPPI]]
*[[taxol|Paclitaxel]]
*[[phaclofen]]
*[[phaclofen]]
*[[PMA]]
*[[PMA]]
*[[PP2]]
*[[PP2]]
*[[primaquin]]
*[[primaquine]]
*[[propythiouracil]]
*[[propylthiouracil]]
*[[quinpirole]]
*[[rapamycin]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[RS67333]]
*[[RS67333]]
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*[[SU6656]]
*[[SU6656]]
*[[Suramin]]
*[[Suramin]]
*[[tautomycin]]
*[[taxol]]
*[[thyroxine (T4)]]
*[[thyroxine (T4)]]
*[[TTNPB]]
*[[TTNPB]]
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*[[Y27632]]
*[[Y27632]]
*[[ZM 447439]]
*[[ZM 447439]]
The Following are in need of standardization and curation
*[[AP1510]]
*[[AR-A014418]]
*[[BHQ]]
*[[b-aminoproprionitrile]]
*[[beclomethasone]]
*[[Butyrate]]
*[[celastrol]]
*[[celecoxib]]
*[[chromanol 293B]]
*[[cytochalasin D]]
*[[colchicine]]
*[[diclofenac]]
*[[etoposide]]
*[[GW843682X]]
*[[latrunculin B]]
*[[methimazole]]
*[[MS222]]
*[[nicardipine]]
*[[Nu6102]]
*[[PTU|propylthiouracil(PTU) inhibits thyroxine]]
*[[purmorphamine]]
*[[Pyrazoleanthrone]]
*[[R(+)BayK 8644]]
*[[RHC80267]]
*[[RL-3]]
*[[SB-431542]]
*[[SB505124]]
*[[TG003]]
*[[Thapsigargin]]
*[[Trichostain A]]
*[[U0126]]
*[[U73122]]
*[[Echinomycin]]
*[[Gö 6983]]


==List of Molecules Affecting Specific Pathways==
==List of Molecules Affecting Specific Pathways==
===cAMP===
===cAMP===
[[IBMX]]
*[[IBMX]]
*[[RU486]]
 
===CDK/Cyclins===
*[[olomoucine]]
 
===ERK/MAPK===
===ERK/MAPK===
*[[U0126]]
===JAK/STAT===
===JAK/STAT===
*[[AZD1480]]
*[[AZD1480]]
===JNK===
===JNK===
[[SP600125]]
*[[SP600125]]
*[[Pyrazoleanthrone]]
 
===Nitric Oxide===
*[[sodium nitroprusside]]


===PDGF===
===PDGF===
*[[AG1296]]
*[[AG1296]]
*[[AP1510]]
===Retinoic Acid===
===Retinoic Acid===
*[[AGN193109]]
*[[AGN193109]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[TTNPB]]
*[[TTNPB]]
===Shh===
===Shh===
*[[cyclopamine]]
*[[cyclopamine]]
*[[mHip]]
*[[purmorphamine]]
 
===TGF-beta/BMP===
===TGF-beta/BMP===
*[[SB-431542]]
*[[SB505124]]
===Thyroid Signaling===
*[[PTU]]
===Wnt===
===Wnt===
*[[LiCl]]
*[[LiCl]]


===Epigenetics===
===Epigenetics===
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*[[GM6001|GM6001 (MMP inhibitor)]]
*[[GM6001|GM6001 (MMP inhibitor)]]
*[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]]
*[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]]
 
*[[BB-94|BB-94 MMP inhibitor]]
 
*[[GI254023X| GI254023X MMP10 inhibitor]]
 
 
 


==Small Molecules by Biological Function==
==Small Molecules by Biological Function==
===Angiogenesis===
===Angiogenesis===
*[[herbimycin A]]
*[[herbimycin A]]
*[[Suramin]]
===Apoptosis===
*[[cycloheximide]]
*[[alpha-amanitin]]
*[[Cyclosporin A]]
*[[2,2ʹ-Methylenebis(1,3-cyclohexanedione)]]


===Autophagy===
===Autophagy===
*[[LY-294002]]
*[[LY-294002]]
===Calcium Signaling===
*[[nifedipine]]
*[[R(+)BayK 8644]]
*[[nicardipine]]
*[[deltamethrin]]
*[[BHQ]]
*[[Thapsigargin]]
===Circadian Rhythm===
*[[quinpirole]]
===Cytoskeletal Inhibitors===
===Cytoskeletal Inhibitors===
*[[Cytochalasin B]]
*[[Cytochalasin B]]
*[[cytochalasin D]]
*[[Colcemide]]
*[[jasplakinolide]] is an activator
*[[taxol]]
*[[taxol|Paclitaxel]]
===Cell Cycle, including mitosis===
*[[olomoucine]]
*[[Colcemide]]
===DNA Damage/Repair===
*[[etoposide]]


===Growth Cone, Filopodia, and other Cytoskeletal projections===
===Growth Cone, Filopodia, and other Cytoskeletal projections===
*[[PP2]]
*[[PP2]]
*[[SU6656]]
*[[SU6656]]
*[[cytochalasin D]] 0.1 uM Sigma
*[[latrunculin B]] 30nM Sigma
*[[colchicine]] 12.5uM Sigma
*[[nocodazole]] 0.1uM Sigma
*[[RHC80267]]
===Hatching===
*[[ouabain]]


===Metamorphosis===
===Metamorphosis===
*[[3,3,5-triiodothyronine (T3)]]
*[[3,3,5-triiodothyronine (T3)]]
*[[methimazole]]
*[[propylthiouracil]]
*[[thyroxine (T4)]]
*[[thyroxine (T4)]]


===Neurotransmission===
===Neurotransmission===
*[[diazepam]]
*[[diazepam]]
*[[p-MPPI]]
*[[phaclofen]]
*[[RS67333]]
*[[deltamethrin]]
===Protein Recycling===
*[[primaquine]]
==Drugs by Gene Class==


==Drugs by Molecular Class==
===Channels, including ATPases===
*[[ouabain]]
===G Protein Receptors===
===G Protein Receptors===
*[[purmorphamine]]
===Kinases===
===Kinases===
*[[KT 5720]]
*[[KT 5720]]
*[[olomoucine]]
*[[SB 203580]]
*[[Y27632]]
*[[ZM 447439]]
===Phosphatases===
*[[Cyclosporin A]]
*[[deltamethrin]]
*[[okadaic acid]]
*[[tautomycin]]
===Small GTPases===
===Small GTPases===




===Protein Synthesis===
*[[anisomycin]] 40uM Sigma
*[[cycloheximide]] 40uM


==Textpresso Small Molecules to Research==
==Textpresso Small Molecules to Research==

Revision as of 06:46, 19 May 2016

Notice to our users

Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.

Important small molecule references

Alphabetical List of Small Molecules With Literature References

The Following are in need of standardization and curation

List of Molecules Affecting Specific Pathways

cAMP

CDK/Cyclins

ERK/MAPK

JAK/STAT

JNK

Nitric Oxide

PDGF

Retinoic Acid

Shh

TGF-beta/BMP

Thyroid Signaling

Wnt

Epigenetics

Protease Inhibitors

Small Molecules by Biological Function

Angiogenesis

Apoptosis

Autophagy

Calcium Signaling

Circadian Rhythm

Cytoskeletal Inhibitors

Cell Cycle, including mitosis

DNA Damage/Repair

Growth Cone, Filopodia, and other Cytoskeletal projections

Hatching

Metamorphosis

Neurotransmission

Protein Recycling

Drugs by Gene Class

Channels, including ATPases

G Protein Receptors

Kinases

Phosphatases

Small GTPases

Protein Synthesis

Textpresso Small Molecules to Research

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