XB-MORPHOLINO-17250414 and Small Molecules for Xenopus Research: Difference between pages
(Difference between pages)
imported>Kevin (Created page with "changed from name st6galnac3 MO1 due to author's original intent. BLAST does not link this MO to pard3. The targets listed are for st6galnac3 and need to be refreshed with a...") |
imported>Xenbase |
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==Notice to our users== | |||
Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email. | |||
==Important small molecule references== | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=47903 Wnt/Notch by Myers and Krieg 2014] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=970 Ubiquitin-proteasome by Salic and King 2005] | |||
==Alphabetical List of Small Molecules With Literature References== | |||
*[[1,3-Dicyclohexylurea]] | |||
*[[11-cis retinal]] | |||
*[[18alpha-glycyrretinic acid]] | |||
*[[2'-deoxyadenosine]] | |||
*[[2-APB]] | |||
*[[3,3,5-triiodothyronine (T3)]] | |||
*[[5HT (seratonin)]] | |||
*[[8-Pcpt-2-O-Me-cAMP-AM]] | |||
*[[activin]] | |||
*[[AG1296]] | |||
*[[AG1879]] | |||
*[[AGN193109]] | |||
*[[alpha-amanitin]] | |||
*[[anandamide]] | |||
*[[apelin]] | |||
*[[aphidicolin]] | |||
*[[AZD1480]] | |||
*[[Bafilomycin A1]] | |||
*[[BAPTA-AM]] | |||
*[[Barasertib]] | |||
*[[Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)]] | |||
*[[beta-xyloside]] | |||
*[[blebbistatin]] | |||
*[[BMS-453]] | |||
*[[Brefeldin A (BFA)]] | |||
*[[bumetanide]] | |||
*[[calcium ionophore]] | |||
*[[CGP54626 ]] | |||
*[[Chelerythrine]] | |||
*[[chenodeoxycholic acid]] | |||
*[[chymostatin ]] | |||
*[[Citral]] | |||
*[[Colcemide]] | |||
*[[concanamycin]] | |||
*[[cycloheximide]] | |||
*[[cyclopamine]] | |||
*[[Cyclosporin A]] | |||
*[[Cytochalasin B]] | |||
*[[cytochalasin D]] | |||
*[[D-AP5]] | |||
*[[D-NAME]] | |||
*[[Colcemide|Demecolcine]] | |||
*[[deltamethrin]] | |||
*[[dexamethosone]] | |||
*[[DHT(dihydrotestosterone)]] | |||
*[[diazepam]] | |||
*[[Difopein]] | |||
*[[Diphenyleneiodonium Chloride]] | |||
*[[DMH-1]] | |||
*[[Dorsomorphin]] | |||
*[[DRB]] | |||
*[[Ex-527]] | |||
*[[finasteride]] | |||
*[[folic acid]] | |||
*[[forskolin]] | |||
*[[fusicoccin]] | |||
*[[gallein]] | |||
*[[gentamycin]] | |||
*[[GSK3-inhibitor IX (BIO)]] | |||
*[[GM6001]] | |||
*[[H-89 Dihydrochloride]] | |||
*[[heptanol]] | |||
*[[herbimycin A]] | |||
*[[Hydroxyurea]] | |||
*[[IBMX]] | |||
*[[jasplakinolide]] | |||
*[[6-B345TTQ]] | |||
*[[KT 5720]] | |||
*[[L-NAME]] | |||
*[[lansoprazole]] | |||
*[[latrunculin A]] | |||
*[[latrunculin B]] | |||
*[[LDN-193189]] | |||
*[[leucovorin]] | |||
*[[LiCl]] | |||
*[[LY294002]] | |||
*[[m-3M3FBS]] | |||
*[[methotrexate (MTX)]] | |||
*[[metronidazole]] | |||
*[[Mg132]] | |||
*[[MMP-2 inhibitor II]] | |||
*[[MS-275]] | |||
*[[nicorandil]] | |||
*[[Nicotinamide]] | |||
*[[Nicotinic acid]] | |||
*[[nifedipine]] | |||
*[[nocodazole]] | |||
*[[NSC-87877]] | |||
*[[o-phenanthroline]] | |||
*[[okadaic acid]] | |||
*[[olomoucine]] | |||
*[[ouabain]] | |||
*[[PD173074]] | |||
*[[PD-407824]] | |||
*[[p-MPPI]] | |||
*[[taxol|Paclitaxel]] | |||
*[[phaclofen]] | |||
*[[Picropodophyllin]] | |||
*[[PMA]] | |||
*[[PP2]] | |||
*[[primaquine]] | |||
*[[Progesterone]] | |||
*[[propylthiouracil]] | |||
*[[pyrimethamine]] | |||
*[[quinpirole]] | |||
*[[rac1 inhibitor]] | |||
*[[rapamycin]] | |||
*[[retinoic acid]] | |||
*[[Retinol]] | |||
*[[RO-3306]] | |||
*[[RS67333]] | |||
*[[RU486]] | |||
*[[SAHA]] | |||
*[[SB 203580]] | |||
*[[SB431542]] | |||
*[[SB 505124]] | |||
*[[SCH28080]] | |||
*[[SNAP]] | |||
*[[sodium nitroprusside]] | |||
*[[SP600125 ]] | |||
*[[SU5402]] | |||
*[[SU6656]] | |||
*[[Suramin]] | |||
*[[tautomycin]] | |||
*[[taxol]] | |||
*[[thyroxine (T4)]] | |||
*[[Torin 2]] | |||
*[[Trichostatin A]] | |||
*[[trimetrexate]] | |||
*[[TTNPB]] | |||
*[[Tubercidin]] | |||
*[[tunicamycin]] | |||
*[[Tyrphostin AG 1478]] | |||
*[[U73122]] | |||
*[[Y27632]] | |||
*[[ZM 447439]] | |||
The Following are in need of standardization and curation | |||
*[[AM251]] | |||
*[[AM281]] | |||
*[[AP1510]] | |||
*[[AR-A014418]] | |||
*[[BHQ]] | |||
*[[b-aminoproprionitrile]] | |||
*[[beclomethasone]] | |||
*[[Butyrate]] | |||
*[[calcicludine]] | |||
*[[Calyculin A]] | |||
*[[celastrol]] | |||
*[[celecoxib]] | |||
*[[chromanol 293B]] | |||
*[[chlorate]] | |||
*[[cytochalasin D]] | |||
*[[colchicine]] | |||
*[[dimethyloxallyl glycine (DMOG)]] | |||
*[[diclofenac]] | |||
*[[etoposide]] | |||
*[[IWR1]] | |||
*[[GW843682X]] | |||
*[[leptomycin B]] | |||
*[[LY320135]] | |||
*[[methylcellulose (MC)]] | |||
*[[methimazole]] | |||
*[[MBCD or MBetaCD]] | |||
*[[MS222]] | |||
*[[nicardipine]] | |||
*[[Nu6102]] | |||
*[[phenylthiourea|phenylthiourea (PTU)]] | |||
*[[purmorphamine]] | |||
*[[Pyrazoleanthrone]] | |||
*[[R(+)BayK 8644]] | |||
*[[RHC80267]] | |||
*[[RL-3]] | |||
*[[SAG]] | |||
*[[SB-431542]] | |||
*[[TG003]] | |||
*[[Thapsigargin]] | |||
*[[U0126]] | |||
*[[ursodeoxycholic acid]] | |||
*[[Echinomycin]] | |||
*[[Gö 6983]] | |||
*[[phenylhydrazine]] | |||
*[[ω-conotoxin–GVIA]] | |||
*[[flunarizine]] | |||
*[[tetrodotoxin]] | |||
*[[veratridine]] | |||
*[[NBI-27914]] | |||
==Small Molecules Affecting Pathways== | |||
===cAMP=== | |||
*[[IBMX]] | |||
*[[RU486]] | |||
===CDK/Cyclins=== | |||
*[[olomoucine]] | |||
*[[RO-3306]] | |||
===ERK/MAPK=== | |||
*[[U0126]] | |||
===Folic Acid=== | |||
*[[Methotrexate (MTX)]] | |||
===JAK/STAT=== | |||
*[[AZD1480]] | |||
===JNK=== | |||
*[[SP600125]] | |||
*[[Pyrazoleanthrone]] | |||
===Nitric Oxide=== | |||
*[[sodium nitroprusside]] | |||
===PDGF=== | |||
*[[AG1296]] | |||
*[[AP1510]] | |||
===Retinoic Acid=== | |||
*[[AGN193109]] | |||
*[[Citral]] | |||
*[[retinoic acid]] | |||
*[[Retinol]] | |||
*[[TTNPB]] | |||
*[[BMS-453]] | |||
===Shh=== | |||
*[[cyclopamine]] | |||
*[[purmorphamine]] | |||
*[[Vismodegib]] | |||
===TGF-beta/BMP=== | |||
*[[SB-431542]] | |||
*[[SB505124]] | |||
===Thyroid Signaling=== | |||
*[[PTU]] | |||
===Wnt=== | |||
*[[LiCl]] | |||
*[[GSK3-inhibitor IX (BIO)]] | |||
*[[IWR1]] | |||
===Epigenetics=== | |||
*[[Ex-527]] | |||
===Protease Inhibitors=== | |||
*[[chymostatin]] | |||
*[[GM6001|GM6001 (MMP inhibitor)]] | |||
*[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]] | |||
*[[BB-94|BB-94 MMP inhibitor]] | |||
*[[GI254023X| GI254023X MMP10 inhibitor]] | |||
==Small Molecules affecting Biological Functions & Processes== | |||
===Angiogenesis=== | |||
*[[dimethyloxallyl glycine (DMOG)]] | |||
*[[herbimycin A]] | |||
*[[Suramin]] | |||
===Apoptosis=== | |||
*[[cycloheximide]] | |||
*[[alpha-amanitin]] | |||
*[[Cyclosporin A]] | |||
*[[2,2ʹ-Methylenebis(1,3-cyclohexanedione)]] | |||
*[[NS3694]] | |||
===Autophagy=== | |||
*[[LY-294002]] | |||
===Calcium Signaling=== | |||
*[[nifedipine]] | |||
*[[R(+)BayK 8644]] | |||
*[[nicardipine]] | |||
*[[deltamethrin]] | |||
*[[BHQ]] | |||
*[[Thapsigargin]] | |||
===Circadian Rhythm=== | |||
*[[quinpirole]] | |||
===Cytoskeletal Inhibitors=== | |||
*[[Cytochalasin B]] | |||
*[[cytochalasin D]] | |||
*[[Colcemide]] | |||
*[[jasplakinolide]] is an activator | |||
*[[latrunculin B]] | |||
*[[taxol]] | |||
*[[taxol|Paclitaxel]] | |||
===Cell Cycle, including mitosis=== | |||
*[[Colcemide]] | |||
*[[Hydroxyurea]] | |||
*[[olomoucine]] | |||
*[[PD-407824]] | |||
===Cilia=== | |||
*[[methylcellulose (MC)]] | |||
===DNA Damage/Repair=== | |||
*[[etoposide]] | |||
*[[Hydroxyurea]] | |||
===DNA Synthesis=== | |||
*[[Calyculin A]] | |||
===Growth Cone, Filopodia, and other Cytoskeletal projections=== | |||
*[[PP2]] | |||
*[[SU6656]] | |||
*[[cytochalasin D]] 0.1 uM Sigma | |||
*[[latrunculin B]] 30nM Sigma | |||
*[[colchicine]] 12.5uM Sigma | |||
*[[nocodazole]] 0.1uM Sigma | |||
*[[RHC80267]] | |||
===Hatching=== | |||
*[[ouabain]] | |||
===Left-Right Patterning=== | |||
*[[methylcellulose (MC)]] | |||
===Metamorphosis=== | |||
*[[3,3,5-triiodothyronine (T3)]] | |||
*[[methimazole]] | |||
*[[propylthiouracil]] | |||
*[[thyroxine (T4)]] | |||
===Neurotransmission=== | |||
*[[diazepam]] | |||
*[[p-MPPI]] | |||
*[[phaclofen]] | |||
*[[RS67333]] | |||
*[[deltamethrin]] | |||
===Protein Recycling=== | |||
*[[primaquine]] | |||
==Drugs by Gene Class== | |||
===Channels, including ATPases=== | |||
*[[ouabain]] | |||
*[[AM251]] | |||
*[[AM281]] | |||
*[[LY320135]] | |||
===G Protein Receptors=== | |||
*[[purmorphamine]] | |||
===Kinases=== | |||
*[[KT 5720]] | |||
*[[olomoucine]] | |||
*[[PD-407824]] | |||
*[[SB 203580]] | |||
*[[Y27632]] | |||
*[[ZM 447439]] | |||
===Phosphatases=== | |||
*[[Cyclosporin A]] | |||
*[[deltamethrin]] | |||
*[[okadaic acid]] | |||
*[[tautomycin]] | |||
*[[Calyculin A]] | |||
===Small GTPases=== | |||
===Protein Synthesis=== | |||
*[[anisomycin]] 40uM Sigma | |||
*[[cycloheximide]] 40uM | |||
===Retinoids=== | |||
*[[TTNPB]] Sigma | |||
==Textpresso Small Molecules to Research== | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=43038 importazole inhibits importin] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 M119] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 GBG or GBetaGamma or G Protein Beta Gamma] | |||
*[[LY-294002| LY-294002 inhibits PI3K and autophagy]] | |||
==Models of Anemia== | |||
*[[Phenylhydrazine]] |
Revision as of 08:37, 7 November 2018
Notice to our users
Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.
Important small molecule references
- Database of Small Molecules by Feldman and Hogue 2006 at PubChem
- Wnt/Notch by Myers and Krieg 2014
- Ubiquitin-proteasome by Salic and King 2005
Alphabetical List of Small Molecules With Literature References
- 1,3-Dicyclohexylurea
- 11-cis retinal
- 18alpha-glycyrretinic acid
- 2'-deoxyadenosine
- 2-APB
- 3,3,5-triiodothyronine (T3)
- 5HT (seratonin)
- 8-Pcpt-2-O-Me-cAMP-AM
- activin
- AG1296
- AG1879
- AGN193109
- alpha-amanitin
- anandamide
- apelin
- aphidicolin
- AZD1480
- Bafilomycin A1
- BAPTA-AM
- Barasertib
- Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)
- beta-xyloside
- blebbistatin
- BMS-453
- Brefeldin A (BFA)
- bumetanide
- calcium ionophore
- CGP54626
- Chelerythrine
- chenodeoxycholic acid
- chymostatin
- Citral
- Colcemide
- concanamycin
- cycloheximide
- cyclopamine
- Cyclosporin A
- Cytochalasin B
- cytochalasin D
- D-AP5
- D-NAME
- Demecolcine
- deltamethrin
- dexamethosone
- DHT(dihydrotestosterone)
- diazepam
- Difopein
- Diphenyleneiodonium Chloride
- DMH-1
- Dorsomorphin
- DRB
- Ex-527
- finasteride
- folic acid
- forskolin
- fusicoccin
- gallein
- gentamycin
- GSK3-inhibitor IX (BIO)
- GM6001
- H-89 Dihydrochloride
- heptanol
- herbimycin A
- Hydroxyurea
- IBMX
- jasplakinolide
- 6-B345TTQ
- KT 5720
- L-NAME
- lansoprazole
- latrunculin A
- latrunculin B
- LDN-193189
- leucovorin
- LiCl
- LY294002
- m-3M3FBS
- methotrexate (MTX)
- metronidazole
- Mg132
- MMP-2 inhibitor II
- MS-275
- nicorandil
- Nicotinamide
- Nicotinic acid
- nifedipine
- nocodazole
- NSC-87877
- o-phenanthroline
- okadaic acid
- olomoucine
- ouabain
- PD173074
- PD-407824
- p-MPPI
- Paclitaxel
- phaclofen
- Picropodophyllin
- PMA
- PP2
- primaquine
- Progesterone
- propylthiouracil
- pyrimethamine
- quinpirole
- rac1 inhibitor
- rapamycin
- retinoic acid
- Retinol
- RO-3306
- RS67333
- RU486
- SAHA
- SB 203580
- SB431542
- SB 505124
- SCH28080
- SNAP
- sodium nitroprusside
- SP600125
- SU5402
- SU6656
- Suramin
- tautomycin
- taxol
- thyroxine (T4)
- Torin 2
- Trichostatin A
- trimetrexate
- TTNPB
- Tubercidin
- tunicamycin
- Tyrphostin AG 1478
- U73122
- Y27632
- ZM 447439
The Following are in need of standardization and curation
- AM251
- AM281
- AP1510
- AR-A014418
- BHQ
- b-aminoproprionitrile
- beclomethasone
- Butyrate
- calcicludine
- Calyculin A
- celastrol
- celecoxib
- chromanol 293B
- chlorate
- cytochalasin D
- colchicine
- dimethyloxallyl glycine (DMOG)
- diclofenac
- etoposide
- IWR1
- GW843682X
- leptomycin B
- LY320135
- methylcellulose (MC)
- methimazole
- MBCD or MBetaCD
- MS222
- nicardipine
- Nu6102
- phenylthiourea (PTU)
- purmorphamine
- Pyrazoleanthrone
- R(+)BayK 8644
- RHC80267
- RL-3
- SAG
- SB-431542
- TG003
- Thapsigargin
- U0126
- ursodeoxycholic acid
- Echinomycin
- Gö 6983
- phenylhydrazine
- ω-conotoxin–GVIA
- flunarizine
- tetrodotoxin
- veratridine
- NBI-27914
Small Molecules Affecting Pathways
cAMP
CDK/Cyclins
ERK/MAPK
Folic Acid
JAK/STAT
JNK
Nitric Oxide
PDGF
Retinoic Acid
Shh
TGF-beta/BMP
Thyroid Signaling
Wnt
Epigenetics
Protease Inhibitors
- chymostatin
- GM6001 (MMP inhibitor)
- o-phenanthroline(MMP inhibitor)
- BB-94 MMP inhibitor
- GI254023X MMP10 inhibitor
Small Molecules affecting Biological Functions & Processes
Angiogenesis
Apoptosis
Autophagy
Calcium Signaling
Circadian Rhythm
Cytoskeletal Inhibitors
- Cytochalasin B
- cytochalasin D
- Colcemide
- jasplakinolide is an activator
- latrunculin B
- taxol
- Paclitaxel
Cell Cycle, including mitosis
Cilia
DNA Damage/Repair
DNA Synthesis
Growth Cone, Filopodia, and other Cytoskeletal projections
- PP2
- SU6656
- cytochalasin D 0.1 uM Sigma
- latrunculin B 30nM Sigma
- colchicine 12.5uM Sigma
- nocodazole 0.1uM Sigma
- RHC80267
Hatching
Left-Right Patterning
Metamorphosis
Neurotransmission
Protein Recycling
Drugs by Gene Class
Channels, including ATPases
G Protein Receptors
Kinases
Phosphatases
Small GTPases
Protein Synthesis
- anisomycin 40uM Sigma
- cycloheximide 40uM
Retinoids
- TTNPB Sigma
Textpresso Small Molecules to Research
- importazole inhibits importin
- M119
- GBG or GBetaGamma or G Protein Beta Gamma
- LY-294002 inhibits PI3K and autophagy