Retinoic acid: Difference between revisions

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==Description==
==Description==
[[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."
*-Sigma Product Description
[[File:RetinoicAcid.png|frame|right|Retinoic Acid structure, photo from Sigma-Aldrich]]


==Genes Affected==
==Genes Affected==
*[http://www.xenbase.org/gene/showgene.do?method=display&geneId=480835 rara]


==Suppliers==
==Suppliers==
*[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENBASE]
*[http://www.sigmaaldrich.com/catalog/product/sigma/r2625?lang=en&region=US Sigma]


==Usage Notes==
==Usage Notes==


==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
*[https://pubchem.ncbi.nlm.nih.gov/compound/444795 Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=__________ ____ et al., 2xxxx]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=21398 Drysdale et al., 1991]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50590 Nagy et al., 2015]


>___ Xenbase articles contain a reference to _____ according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>1484 Xenbase articles contain a reference to Retinoic Acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 17:00, 7 March 2016

Description

"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."

  • -Sigma Product Description
Retinoic Acid structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

References

>1484 Xenbase articles contain a reference to Retinoic Acid according to textpresso