Small Molecules for Xenopus Research: Difference between revisions

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==Notice to our users==
Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.
==Important small molecule references==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=47903 Wnt/Notch by Myers and Krieg 2014]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=970 Ubiquitin-proteasome by Salic and King 2005]
==Alphabetical List of Small Molecules With Literature References==
==Alphabetical List of Small Molecules With Literature References==


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*[[activin]]
*[[activin]]
*[[AG1296]]
*[[AG1296]]
*[[AG1879]]
*[[AGN193109]]
*[[AGN193109]]
*[[alpha-amanitin]]
*[[alpha-amanitin]]
*[[anandamide]]
*[[anandamide]]
*[[apelin]]
*[[apelin]]
*[[aphidicolin ]]
*[[aphidicolin]]
*[[AZD1480]]
*[[AZD1480]]
*[[BAPTA-AM]]
*[[BAPTA-AM]]
*[[BMS-453]]
*[[beta-xyloside]]
*[[beta-xyloside]]
*[[bumetanide]]
*[[bumetanide]]
Line 20: Line 30:
*[[Chelerythrine]]
*[[Chelerythrine]]
*[[chymostatin ]]
*[[chymostatin ]]
*[[Colcemide]]
*[[concanamycin]]
*[[concanamycin]]
*[[cycloheximide]]
*[[cycloheximide]]
*[[cyclopamine]]
*[[cyclopamine]]
*[[Cyclosporin A]]
*[[Cytochalasin B]]
*[[Cytochalasin B]]
*[[cytochalasin D]]
*[[Colcemide|Demecolcine]]
*[[deltamethrin]]
*[[dexamethosone]]
*[[dexamethosone]]
*[[DHT(dihydrotestosterone)]]
*[[DHT(dihydrotestosterone)]]
*[[diazepam]]
*[[Ex-527]]
*[[Ex-527]]
*[[forskolin]]
*[[forskolin]]
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*[[GM6001]]
*[[GM6001]]
*[[heptanol]]
*[[heptanol]]
*[[herbimycin A]]
*[[IBMX]]
*[[IBMX]]
*[[jasplakinolide]]
*[[KT 5720]]
*[[KT 5720]]
*[[lansoprazol]]
*[[lansoprazole]]
*[[LiCl]]
*[[LiCl]]
*[[Mg132]]
*[[Mg132]]
*[[mHip]]
*[[MMP-2 inhibitor II]]
*[[MMP-2 inhibitor II]]
*[[nicorandil]]
*[[nicorandil]]
Line 44: Line 61:
*[[NSC-87877]]
*[[NSC-87877]]
*[[o-phenanthroline]]
*[[o-phenanthroline]]
*[[okadaic acid]]
*[[olomoucine]]
*[[olomoucine]]
*[[ouabain]]
*[[ouabain]]
*[[PD-407824]]
*[[p-MPPI]]
*[[p-MPPI]]
*[[taxol|Paclitaxel]]
*[[phaclofen]]
*[[phaclofen]]
*[[PMA]]
*[[PMA]]
*[[primaquin]]
*[[PP2]]
*[[propythiouracil]]
*[[primaquine]]
*[[propylthiouracil]]
*[[quinpirole]]
*[[rapamycin]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[RS67333]]
*[[RS67333]]
*[[RU486]]
*[[RU486]]
*[[SB 203580]]
*[[SB 203580]]
*[[SCH28080]]
*[[sodium nitroprusside]]
*[[sodium nitroprusside]]
*[[SP600125 ]]
*[[SP600125 ]]
*[[SU5402]]
*[[SU5402]]
*[[SU6656]]
*[[Suramin]]
*[[Suramin]]
*[[tautomycin]]
*[[taxol]]
*[[thyroxine (T4)]]
*[[thyroxine (T4)]]
*[[TTNPB]]
*[[TTNPB]]
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*[[Y27632]]
*[[Y27632]]
*[[ZM 447439]]
*[[ZM 447439]]
The Following are in need of standardization and curation
*[[AP1510]]
*[[AR-A014418]]
*[[BHQ]]
*[[b-aminoproprionitrile]]
*[[beclomethasone]]
*[[Butyrate]]
*[[celastrol]]
*[[celecoxib]]
*[[chromanol 293B]]
*[[cytochalasin D]]
*[[colchicine]]
*[[diclofenac]]
*[[etoposide]]
*[[GW843682X]]
*[[latrunculin B]]
*[[methimazole]]
*[[MBCD or MBetaCD]]
*[[MS222]]
*[[nicardipine]]
*[[Nu6102]]
*[[PTU|propylthiouracil(PTU) inhibits thyroxine]]
*[[PTU|phenylthiouracil(PTU inhibits melanophore formation]]
*[[purmorphamine]]
*[[Pyrazoleanthrone]]
*[[R(+)BayK 8644]]
*[[RHC80267]]
*[[RL-3]]
*[[SB-431542]]
*[[SB505124]]
*[[TG003]]
*[[Thapsigargin]]
*[[Trichostain A]]
*[[U0126]]
*[[U73122]]
*[[Echinomycin]]
*[[Gö 6983]]
*[[phenylhydrazine]]


==List of Molecules Affecting Specific Pathways==
==List of Molecules Affecting Specific Pathways==
===cAMP===
===cAMP===
[[IBMX]]
*[[IBMX]]
*[[RU486]]
 
===CDK/Cyclins===
*[[olomoucine]]
 
===ERK/MAPK===
===ERK/MAPK===
*[[U0126]]
===JAK/STAT===
===JAK/STAT===
*[[AZD1480]]
*[[AZD1480]]
===JNK===
===JNK===
[[SP600125]]
*[[SP600125]]
*[[Pyrazoleanthrone]]
 
===Nitric Oxide===
*[[sodium nitroprusside]]


===PDGF===
===PDGF===
*[[AG1296]]
*[[AG1296]]
*[[AP1510]]
===Retinoic Acid===
===Retinoic Acid===
*[[AGN193109]]
*[[AGN193109]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[TTNPB]]
*[[TTNPB]]
*[[BMS-453]]
===Shh===
===Shh===
*[[cyclopamine]]
*[[cyclopamine]]
*[[mHip]]
*[[purmorphamine]]
 
===TGF-beta/BMP===
===TGF-beta/BMP===
*[[SB-431542]]
*[[SB505124]]
===Thyroid Signaling===
*[[PTU]]
===Wnt===
===Wnt===
*[[LiCl]]
*[[LiCl]]


===Cytoskeletal Inhibitors===
*[[Cytochalasin B]]
===Epigenetics===
===Epigenetics===
[[Ex-527]]
*[[Ex-527]]
 
===Protease Inhibitors===
===Protease Inhibitors===
*[[chymostatin]]
*[[chymostatin]]
*[[GM6001|GM6001 (MMP inhibitor)]]
*[[GM6001|GM6001 (MMP inhibitor)]]
*[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]]
*[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]]
*[[BB-94|BB-94 MMP inhibitor]]
*[[GI254023X| GI254023X MMP10 inhibitor]]


==Small Molecules by Biological Function==
===Angiogenesis===
*[[herbimycin A]]
*[[Suramin]]


===Small Molecules Studied in Oocytes Found Via Textpresso===
===Apoptosis===
*[[cycloheximide]]
*[[alpha-amanitin]]
*[[Cyclosporin A]]
*[[2,2ʹ-Methylenebis(1,3-cyclohexanedione)]]
*[[NS3694]]
 
===Autophagy===
*[[LY-294002]]
 
===Calcium Signaling===
*[[nifedipine]]
*[[R(+)BayK 8644]]
*[[nicardipine]]
*[[deltamethrin]]
*[[BHQ]]
*[[Thapsigargin]]
 
===Circadian Rhythm===
*[[quinpirole]]
 
===Cytoskeletal Inhibitors===
*[[Cytochalasin B]]
*[[cytochalasin D]]
*[[Colcemide]]
*[[jasplakinolide]] is an activator
*[[taxol]]
*[[taxol|Paclitaxel]]
 
===Cell Cycle, including mitosis===
*[[Colcemide]]
*[[olomoucine]]
*[[PD-407824]]
 
===DNA Damage/Repair===
*[[etoposide]]
 
===Growth Cone, Filopodia, and other Cytoskeletal projections===
*[[PP2]]
*[[SU6656]]
*[[cytochalasin D]] 0.1 uM Sigma
*[[latrunculin B]] 30nM Sigma
*[[colchicine]] 12.5uM Sigma
*[[nocodazole]] 0.1uM Sigma
*[[RHC80267]]
 
===Hatching===
*[[ouabain]]
 
===Metamorphosis===
*[[3,3,5-triiodothyronine (T3)]]
*[[methimazole]]
*[[propylthiouracil]]
*[[thyroxine (T4)]]
 
===Neurotransmission===
*[[diazepam]]
*[[p-MPPI]]
*[[phaclofen]]
*[[RS67333]]
*[[deltamethrin]]
 
===Protein Recycling===
*[[primaquine]]
 
==Drugs by Gene Class==
 
===Channels, including ATPases===
*[[ouabain]]
===G Protein Receptors===
*[[purmorphamine]]
===Kinases===
*[[KT 5720]]
*[[olomoucine]]
*[[PD-407824]]
*[[SB 203580]]
*[[Y27632]]
*[[ZM 447439]]
 
===Phosphatases===
*[[Cyclosporin A]]
*[[deltamethrin]]
*[[okadaic acid]]
*[[tautomycin]]
 
===Small GTPases===
 
 
===Protein Synthesis===
*[[anisomycin]] 40uM Sigma
*[[cycloheximide]] 40uM
 
==Textpresso Small Molecules to Research==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=43038 importazole inhibits importin]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 M119]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 M119]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 GBG or GBetaGamma]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 GBG or GBetaGamma or G Protein Beta Gamma]
*[[LY-294002| LY-294002 inhibits PI3K and autophagy]]
 
==Models of Anemia==
*[phenylhydrazine]

Revision as of 12:56, 8 August 2016

Notice to our users

Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.

Important small molecule references

Alphabetical List of Small Molecules With Literature References

The Following are in need of standardization and curation

List of Molecules Affecting Specific Pathways

cAMP

CDK/Cyclins

ERK/MAPK

JAK/STAT

JNK

Nitric Oxide

PDGF

Retinoic Acid

Shh

TGF-beta/BMP

Thyroid Signaling

Wnt

Epigenetics

Protease Inhibitors

Small Molecules by Biological Function

Angiogenesis

Apoptosis

Autophagy

Calcium Signaling

Circadian Rhythm

Cytoskeletal Inhibitors

Cell Cycle, including mitosis

DNA Damage/Repair

Growth Cone, Filopodia, and other Cytoskeletal projections

Hatching

Metamorphosis

Neurotransmission

Protein Recycling

Drugs by Gene Class

Channels, including ATPases

G Protein Receptors

Kinases

Phosphatases

Small GTPases

Protein Synthesis

Textpresso Small Molecules to Research

Models of Anemia

  • [phenylhydrazine]
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