imported>Mfisher |
imported>Kevin |
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| ==Notice to our users==
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| Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email.
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| ==Important small molecule references==
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem]
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=47903 Wnt/Notch by Myers and Krieg 2014]
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=970 Ubiquitin-proteasome by Salic and King 2005]
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|
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| ==Alphabetical List of Small Molecules With Literature References==
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|
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| *[[11-cis retinal]]
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| *[[18alpha-glycyrretinic acid]]
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| *[[3,3,5-triiodothyronine (T3)]]
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| *[[5HT (seratonin)]]
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| *[[activin]]
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| *[[AG1296]]
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| *[[AG1879]]
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| *[[AGN193109]]
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| *[[alpha-amanitin]]
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| *[[anandamide]]
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| *[[apelin]]
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| *[[aphidicolin]]
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| *[[AZD1480]]
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| *[[BAPTA-AM]]
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| *[[BMS-453]]
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| *[[beta-xyloside]]
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| *[[bumetanide]]
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| *[[calcium ionophore]]
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| *[[CGP54626 ]]
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| *[[Chelerythrine]]
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| *[[chymostatin ]]
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| *[[Colcemide]]
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| *[[concanamycin]]
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| *[[cycloheximide]]
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| *[[cyclopamine]]
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| *[[Cyclosporin A]]
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| *[[Cytochalasin B]]
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| *[[cytochalasin D]]
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| *[[Colcemide|Demecolcine]]
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| *[[deltamethrin]]
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| *[[dexamethosone]]
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| *[[DHT(dihydrotestosterone)]]
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| *[[diazepam]]
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| *[[Ex-527]]
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| *[[forskolin]]
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| *[[fusicoccin]]
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| *[[gentamycin]]
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| *[[GM6001]]
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| *[[heptanol]]
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| *[[herbimycin A]]
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| *[[IBMX]]
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| *[[jasplakinolide]]
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| *[[KT 5720]]
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| *[[lansoprazole]]
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| *[[LiCl]]
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| *[[Mg132]]
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| *[[MMP-2 inhibitor II]]
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| *[[nicorandil]]
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| *[[nifedipine]]
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| *[[nocodazole]]
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| *[[NSC-87877]]
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| *[[o-phenanthroline]]
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| *[[okadaic acid]]
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| *[[olomoucine]]
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| *[[ouabain]]
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| *[[PD-407824]]
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| *[[p-MPPI]]
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| *[[taxol|Paclitaxel]]
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| *[[phaclofen]]
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| *[[PMA]]
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| *[[PP2]]
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| *[[primaquine]]
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| *[[propylthiouracil]]
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| *[[quinpirole]]
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| *[[rapamycin]]
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| *[[retinoic acid]]
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| *[[RS67333]]
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| *[[RU486]]
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| *[[SB 203580]]
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| *[[SCH28080]]
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| *[[sodium nitroprusside]]
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| *[[SP600125 ]]
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| *[[SU5402]]
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| *[[SU6656]]
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| *[[Suramin]]
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| *[[tautomycin]]
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| *[[taxol]]
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| *[[thyroxine (T4)]]
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| *[[TTNPB]]
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| *[[tunicamycin]]
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| *[[Y27632]]
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| *[[ZM 447439]]
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|
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| The Following are in need of standardization and curation
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| *[[AP1510]]
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| *[[AR-A014418]]
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| *[[BHQ]]
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| *[[b-aminoproprionitrile]]
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| *[[beclomethasone]]
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| *[[Butyrate]]
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| *[[celastrol]]
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| *[[celecoxib]]
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| *[[chromanol 293B]]
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| *[[cytochalasin D]]
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| *[[colchicine]]
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| *[[diclofenac]]
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| *[[etoposide]]
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| *[[GW843682X]]
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| *[[latrunculin B]]
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| *[[methimazole]]
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| *[[MBCD or MBetaCD]]
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| *[[MS222]]
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| *[[nicardipine]]
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| *[[Nu6102]]
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| *[[PTU|propylthiouracil(PTU) inhibits thyroxine]]
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| *[[PTU|phenylthiouracil(PTU inhibits melanophore formation]]
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| *[[purmorphamine]]
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| *[[Pyrazoleanthrone]]
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| *[[R(+)BayK 8644]]
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| *[[RHC80267]]
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| *[[RL-3]]
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| *[[SB-431542]]
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| *[[SB505124]]
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| *[[TG003]]
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| *[[Thapsigargin]]
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| *[[Trichostain A]]
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| *[[U0126]]
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| *[[U73122]]
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| *[[Echinomycin]]
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| *[[Gö 6983]]
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| *[[phenylhydrazine]]
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|
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| ==List of Molecules Affecting Specific Pathways==
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| ===cAMP===
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| *[[IBMX]]
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| *[[RU486]]
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| ===CDK/Cyclins===
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| *[[olomoucine]]
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|
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| ===ERK/MAPK===
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| *[[U0126]]
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|
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| ===JAK/STAT===
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| *[[AZD1480]]
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|
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| ===JNK===
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| *[[SP600125]]
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| *[[Pyrazoleanthrone]]
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|
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| ===Nitric Oxide===
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| *[[sodium nitroprusside]]
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|
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| ===PDGF===
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| *[[AG1296]]
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| *[[AP1510]]
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|
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| ===Retinoic Acid===
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| *[[AGN193109]]
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| *[[retinoic acid]]
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| *[[TTNPB]]
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| *[[BMS-453]]
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|
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| ===Shh===
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| *[[cyclopamine]]
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| *[[purmorphamine]]
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|
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| ===TGF-beta/BMP===
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| *[[SB-431542]]
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| *[[SB505124]]
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|
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| ===Thyroid Signaling===
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| *[[PTU]]
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| ===Wnt===
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| *[[LiCl]]
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| ===Epigenetics===
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| *[[Ex-527]]
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| ===Protease Inhibitors===
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| *[[chymostatin]]
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| *[[GM6001|GM6001 (MMP inhibitor)]]
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| *[[o-phenanthroline|o-phenanthroline(MMP inhibitor)]]
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| *[[BB-94|BB-94 MMP inhibitor]]
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| *[[GI254023X| GI254023X MMP10 inhibitor]]
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| ==Small Molecules by Biological Function==
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| ===Angiogenesis===
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| *[[herbimycin A]]
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| *[[Suramin]]
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| ===Apoptosis===
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| *[[cycloheximide]]
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| *[[alpha-amanitin]]
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| *[[Cyclosporin A]]
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| *[[2,2ʹ-Methylenebis(1,3-cyclohexanedione)]]
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| *[[NS3694]]
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|
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| ===Autophagy===
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| *[[LY-294002]]
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| ===Calcium Signaling===
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| *[[nifedipine]]
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| *[[R(+)BayK 8644]]
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| *[[nicardipine]]
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| *[[deltamethrin]]
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| *[[BHQ]]
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| *[[Thapsigargin]]
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|
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| ===Circadian Rhythm===
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| *[[quinpirole]]
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|
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| ===Cytoskeletal Inhibitors===
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| *[[Cytochalasin B]]
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| *[[cytochalasin D]]
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| *[[Colcemide]]
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| *[[jasplakinolide]] is an activator
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| *[[taxol]]
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| *[[taxol|Paclitaxel]]
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|
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| ===Cell Cycle, including mitosis===
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| *[[Colcemide]]
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| *[[olomoucine]]
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| *[[PD-407824]]
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| ===DNA Damage/Repair===
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| *[[etoposide]]
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|
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| ===Growth Cone, Filopodia, and other Cytoskeletal projections===
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| *[[PP2]]
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| *[[SU6656]]
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| *[[cytochalasin D]] 0.1 uM Sigma
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| *[[latrunculin B]] 30nM Sigma
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| *[[colchicine]] 12.5uM Sigma
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| *[[nocodazole]] 0.1uM Sigma
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| *[[RHC80267]]
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|
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| ===Hatching===
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| *[[ouabain]]
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|
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| ===Metamorphosis===
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| *[[3,3,5-triiodothyronine (T3)]]
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| *[[methimazole]]
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| *[[propylthiouracil]]
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| *[[thyroxine (T4)]]
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|
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| ===Neurotransmission===
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| *[[diazepam]]
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| *[[p-MPPI]]
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| *[[phaclofen]]
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| *[[RS67333]]
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| *[[deltamethrin]]
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|
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| ===Protein Recycling===
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| *[[primaquine]]
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|
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| ==Drugs by Gene Class==
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| ===Channels, including ATPases===
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| *[[ouabain]]
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| ===G Protein Receptors===
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| *[[purmorphamine]]
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| ===Kinases===
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| *[[KT 5720]]
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| *[[olomoucine]]
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| *[[PD-407824]]
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| *[[SB 203580]]
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| *[[Y27632]]
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| *[[ZM 447439]]
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|
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| ===Phosphatases===
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| *[[Cyclosporin A]]
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| *[[deltamethrin]]
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| *[[okadaic acid]]
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| *[[tautomycin]]
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|
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| ===Small GTPases===
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| ===Protein Synthesis===
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| *[[anisomycin]] 40uM Sigma
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| *[[cycloheximide]] 40uM
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|
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| ==Textpresso Small Molecules to Research==
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=43038 importazole inhibits importin]
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 M119]
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=42068 GBG or GBetaGamma or G Protein Beta Gamma]
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| *[[LY-294002| LY-294002 inhibits PI3K and autophagy]]
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|
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| ==Models of Anemia==
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| *[phenylhydrazine]
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