Small Molecules for Xenopus Research: Difference between revisions

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==Alphabetical List of Small Molecules With Literature References==
==Alphabetical List of Small Molecules With Literature References==


*[[1,3-Dicyclohexylurea]]
*[[11-cis retinal]]
*[[11-cis retinal]]
*[[18alpha-glycyrretinic acid]]
*[[18alpha-glycyrrhetinic acid]]
*[[2'-deoxyadenosine]]
*[[2-APB]]
*[[2-Deoxyglucose]]
*[[3,3,5-triiodothyronine (T3)]]
*[[3,3,5-triiodothyronine (T3)]]
*[[5HT (seratonin)]]
*[[5HT (seratonin)]]
*[[8-Pcpt-2-O-Me-cAMP-AM]]
*[[activin]]
*[[activin]]
*[[Adenosine, periodate oxidized]]
*[[AG1296]]
*[[AG1296]]
*[[AG1879]]
*[[AG1879]]
*[[AGN193109]]
*[[AGN193109]]
*[[alpha-amanitin]]
*[[alpha-amanitin]]
*[[Alisertib]]
*[[anandamide]]
*[[anandamide]]
*[[AP-III-a4]]
*[[apelin]]
*[[apelin]]
*[[aphidicolin]]
*[[aphidicolin]]
*[[Aroclor 1254]]
*[[Atrazine]]
*[[AZD1480]]
*[[AZD1480]]
*[[Bafilomycin A1]]
*[[BAPTA-AM]]
*[[BAPTA-AM]]
*[[Barasertib]]
*[[Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)]]
*[[beta-xyloside]]
*[[blebbistatin]]
*[[BMS-453]]
*[[BMS-453]]
*[[beta-xyloside]]
*[[Brefeldin A (BFA)]]
*[[bumetanide]]
*[[bumetanide]]
*[[calcium ionophore]]
*[[calcium ionophore]]
*[[canertinib]]
*[[CGP54626 ]]
*[[CGP54626 ]]
*[[Chelerythrine]]
*[[Chelerythrine]]
*[[chenodeoxycholic acid]]
*[[chlorpromazine]]
*[[chymostatin ]]
*[[chymostatin ]]
*[[Citral]]
*[[Colcemide]]
*[[Colcemide]]
*[[concanamycin]]
*[[concanamycin]]
*[[CP-91149]]
*[[cycloheximide]]
*[[cycloheximide]]
*[[cyclopamine]]
*[[cyclopamine]]
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*[[Cytochalasin B]]
*[[Cytochalasin B]]
*[[cytochalasin D]]
*[[cytochalasin D]]
*[[Colcemide|Demecolcine]]
*[[D-AP5]]
*[[D-NAME]]
*[[deltamethrin]]
*[[deltamethrin]]
*[[dexamethosone]]
*[[dexamethosone]]
*[[DHT(dihydrotestosterone)]]
*[[DHT(dihydrotestosterone)]]
*[[diazepam]]
*[[diazepam]]
*[[Difopein]]
*[[Diphenyleneiodonium Chloride]]
*[[DMH-1]]
*[[Dorsomorphin]]
*[[DRB]]
*[[Ex-527]]
*[[Ex-527]]
*[[finasteride]]
*[[folic acid]]
*[[forskolin]]
*[[forskolin]]
*[[fusicoccin]]
*[[fusicoccin]]
*[[gallein]]
*[[GANT 61]]
*[[gentamycin]]
*[[gentamycin]]
*[[GSK3-inhibitor IX (BIO)]]
*[[GM6001]]
*[[GM6001]]
*[[H-89 Dihydrochloride]]
*[[heptanol]]
*[[heptanol]]
*[[herbimycin A]]
*[[herbimycin A]]
*[[Hh-Ag1.8]]
*[[Hydroxyurea]]
*[[IBMX]]
*[[IBMX]]
*[[Iodoacetic acid]]
*[[jasplakinolide]]
*[[jasplakinolide]]
*[[6-B345TTQ]]
*[[Ketamine]]
*[[KT 5720]]
*[[KT 5720]]
*[[L-NAME]]
*[[lansoprazole]]
*[[lansoprazole]]
*[[latrunculin A]]
*[[latrunculin B]]
*[[LDN-193189]]
*[[Leflunomide]]
*[[leucovorin]]
*[[LiCl]]
*[[LiCl]]
*[[Lovastatin]]
*[[LY294002]]
*[[m-3M3FBS]]
*[[methotrexate (MTX)]]
*[[metronidazole]]
*[[Mg132]]
*[[Mg132]]
*[[MK-2206]]
*[[MMP-2 inhibitor II]]
*[[MMP-2 inhibitor II]]
*[[MS-275]]
*[[Mubritinib]]
*[[nicorandil]]
*[[nicorandil]]
*[[Nicotinamide]]
*[[Nicotinic acid]]
*[[nifedipine]]
*[[nifedipine]]
*[[nocodazole]]
*[[nocodazole]]
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*[[olomoucine]]
*[[olomoucine]]
*[[ouabain]]
*[[ouabain]]
*[[Olygomycin]]
*[[PD173074]]
*[[PD-407824]]
*[[PD-407824]]
*[[p-MPPI]]
*[[p-MPPI]]
*[[taxol|Paclitaxel]]
*[[taxol|Paclitaxel]]
*[[phaclofen]]
*[[phaclofen]]
*[[phenylthiourea|phenylthiourea (PTU)]]
*[[Picropodophyllin]]
*[[PMA]]
*[[PMA]]
*[[PP2]]
*[[PP2]]
*[[primaquine]]
*[[primaquine]]
*[[Progesterone]]
*[[propylthiouracil]]
*[[propylthiouracil]]
*[[psoralen]]
*[[pyrimethamine]]
*[[quinpirole]]
*[[quinpirole]]
*[[rac1 inhibitor]]
*[[rapamycin]]
*[[rapamycin]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[Retinol]]
*[[RO-3306]]
*[[RS67333]]
*[[RS67333]]
*[[RU486]]
*[[RU486]]
*[[SAHA]]
*[[SB 203580]]
*[[SB 203580]]
*[[SB431542]]
*[[SB-505124]]
*[[SCH28080]]
*[[SCH28080]]
*[[SNAP]]
*[[sodium nitroprusside]]
*[[sodium nitroprusside]]
*[[sodium perchlorate]]
*[[SP600125 ]]
*[[SP600125 ]]
*[[SU5402]]
*[[SU5402]]
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*[[taxol]]
*[[taxol]]
*[[thyroxine (T4)]]
*[[thyroxine (T4)]]
*[[Torin 2]]
*[[Trichostatin A]]
*[[trimetrexate]]
*[[Triptolide]]
*[[TTNPB]]
*[[TTNPB]]
*[[Tubercidin]]
*[[tunicamycin]]
*[[tunicamycin]]
*[[Tyrphostin AG 1478]]
*[[U73122]]
*[[Y27632]]
*[[Y27632]]
*[[ZM 447439]]
*[[ZM 447439]]


The Following are in need of standardization and curation
The Following are in need of standardization and curation
*[[AM251]]
*[[AM281]]
*[[AP1510]]
*[[AP1510]]
*[[AR-A014418]]
*[[AR-A014418]]
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*[[beclomethasone]]
*[[beclomethasone]]
*[[Butyrate]]
*[[Butyrate]]
*[[calcicludine]]
*[[Calyculin A]]
*[[celastrol]]
*[[celastrol]]
*[[celecoxib]]
*[[celecoxib]]
*[[chromanol 293B]]
*[[chromanol 293B]]
*[[chlorate]]
*[[cytochalasin D]]  
*[[cytochalasin D]]  
*[[colchicine]]
*[[colchicine]]
*[[dimethyloxallyl glycine (DMOG)]]
*[[diclofenac]]
*[[diclofenac]]
*[[etoposide]]
*[[etoposide]]
*[[IWR1]]
*[[GW843682X]]
*[[GW843682X]]
*[[latrunculin B]]
*[[leptomycin B]]
*[[LY320135]]
*[[methylcellulose (MC)]]
*[[methimazole]]
*[[methimazole]]
*[[MBCD or MBetaCD]]
*[[MBCD or MBetaCD]]
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*[[nicardipine]]
*[[nicardipine]]
*[[Nu6102]]
*[[Nu6102]]
*[[PTU|propylthiouracil(PTU) inhibits thyroxine]]
*[[PTU|phenylthiouracil(PTU inhibits melanophore formation]]
*[[purmorphamine]]
*[[purmorphamine]]
*[[Pyrazoleanthrone]]
*[[Pyrazoleanthrone]]
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*[[RHC80267]]
*[[RHC80267]]
*[[RL-3]]
*[[RL-3]]
*[[SAG]]
*[[SB-431542]]
*[[SB-431542]]
*[[SB505124]]
*[[TG003]]
*[[TG003]]
*[[Thapsigargin]]
*[[Thapsigargin]]
*[[Trichostain A]]
*[[U0126]]
*[[U0126]]
*[[U73122]]
*[[ursodeoxycholic acid]]
*[[valproic acid (VPA)]]
*[[Echinomycin]]
*[[Echinomycin]]
*[[Gö 6983]]
*[[Gö 6983]]
*[[phenylhydrazine]]
*[[phenylhydrazine]]
*[[ω-conotoxin–GVIA]]
*[[flunarizine]]
*[[tetrodotoxin]]
*[[veratridine]]
*[[NBI-27914]]


==List of Molecules Affecting Specific Pathways==
==Small Molecules Affecting Pathways==
===cAMP===
===cAMP===
*[[IBMX]]
*[[IBMX]]
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===CDK/Cyclins===
===CDK/Cyclins===
*[[olomoucine]]
*[[olomoucine]]
*[[RO-3306]]
*[[R-roscovitine]]


===ERK/MAPK===
===ERK/MAPK===
*[[U0126]]
*[[U0126]]
===Folic Acid===
*[[Methotrexate (MTX)]]


===JAK/STAT===
===JAK/STAT===
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===Retinoic Acid===
===Retinoic Acid===
*[[AGN193109]]
*[[AGN193109]]
*[[Citral]]
*[[retinoic acid]]
*[[retinoic acid]]
*[[Retinol]]
*[[TTNPB]]
*[[TTNPB]]
*[[BMS-453]]
*[[BMS-453]]
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*[[cyclopamine]]
*[[cyclopamine]]
*[[purmorphamine]]
*[[purmorphamine]]
*[[Hh-Ag1.8]]
*[[Vismodegib]]


===TGF-beta/BMP===
===TGF-beta/BMP===
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===Thyroid Signaling===
===Thyroid Signaling===
*[[PTU]]
*[[NH-3]]


===Wnt===
===Wnt===
*[[LiCl]]
*[[LiCl]]
*[[GSK3-inhibitor IX (BIO)]]
*[[IWR1]]


===Epigenetics===
===Epigenetics===
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*[[GI254023X| GI254023X MMP10 inhibitor]]
*[[GI254023X| GI254023X MMP10 inhibitor]]


==Small Molecules by Biological Function==
==Small Molecules affecting Biological Functions & Processes==
===Angiogenesis===
===Angiogenesis===
*[[dimethyloxallyl glycine (DMOG)]]
*[[herbimycin A]]
*[[herbimycin A]]
*[[Suramin]]
*[[Suramin]]
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*[[cytochalasin D]]
*[[cytochalasin D]]
*[[Colcemide]]
*[[Colcemide]]
*[[Colchicine]]
*[[jasplakinolide]] is an activator
*[[jasplakinolide]] is an activator
*[[latrunculin B]]
*[[taxol]]
*[[taxol]]
*[[taxol|Paclitaxel]]
*[[taxol|Paclitaxel]]
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===Cell Cycle, including mitosis===
===Cell Cycle, including mitosis===
*[[Colcemide]]
*[[Colcemide]]
*[[Hydroxyurea]]
*[[olomoucine]]
*[[PD-407824]]
*[[PD-407824]]
*[[olomoucine]]
===Cell migration, including specific cell lineage removal===
*[[Clodronate]]
 
===Cilia===
*[[methylcellulose (MC)]]


===DNA Damage/Repair===
===DNA Damage/Repair===
*[[etoposide]]
*[[etoposide]]
*[[Hydroxyurea]]
===DNA Synthesis===
*[[Calyculin A]]
===DNA mutagenic compounds===
*[[ENU or N-nitroso-N-ethylurea]] 100mM Sigma N3385


===Growth Cone, Filopodia, and other Cytoskeletal projections===
===Growth Cone, Filopodia, and other Cytoskeletal projections===
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===Hatching===
===Hatching===
*[[ouabain]]
*[[ouabain]]
===Left-Right Patterning===
*[[methylcellulose (MC)]]


===Metamorphosis===
===Metamorphosis===
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===Channels, including ATPases===
===Channels, including ATPases===
*[[ouabain]]
*[[ouabain]]
*[[AM251]]
*[[AM281]]
*[[LY320135]]
*[[bafilomycin A1]]
===G Protein Receptors===
===G Protein Receptors===
*[[purmorphamine]]
*[[purmorphamine]]
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*[[KT 5720]]
*[[KT 5720]]
*[[olomoucine]]
*[[olomoucine]]
*[[PD-407824]]
*[[SB 203580]]
*[[SB 203580]]
*[[Y27632]]
*[[Y27632]]
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*[[okadaic acid]]
*[[okadaic acid]]
*[[tautomycin]]
*[[tautomycin]]
*[[Calyculin A]]


===Small GTPases===
===Small GTPases===
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*[[anisomycin]] 40uM Sigma
*[[anisomycin]] 40uM Sigma
*[[cycloheximide]] 40uM
*[[cycloheximide]] 40uM
===Retinoids===
*[[TTNPB]] Sigma


==Textpresso Small Molecules to Research==
==Textpresso Small Molecules to Research==
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==Models of Anemia==
==Models of Anemia==
*[phenylhydrazine]
*[[Phenylhydrazine]]
==Environmental toxins==
*[[Cis-bifenthrin (cis-BF)]]
*[[Graphine (GO)]]
*[[4-methylcyclohexane methanol (MCHM)]]
*[[4-octylphenol (OP)]]
*[[metamifop]]

Latest revision as of 08:21, 16 May 2023

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Important small molecule references

Alphabetical List of Small Molecules With Literature References

The Following are in need of standardization and curation

Small Molecules Affecting Pathways

cAMP

CDK/Cyclins

ERK/MAPK

Folic Acid

JAK/STAT

JNK

Nitric Oxide

PDGF

Retinoic Acid

Shh

TGF-beta/BMP

Thyroid Signaling

Wnt

Epigenetics

Protease Inhibitors

Small Molecules affecting Biological Functions & Processes

Angiogenesis

Apoptosis

Autophagy

Calcium Signaling

Circadian Rhythm

Cytoskeletal Inhibitors

Cell Cycle, including mitosis

Cell migration, including specific cell lineage removal

Cilia

DNA Damage/Repair

DNA Synthesis

DNA mutagenic compounds


Growth Cone, Filopodia, and other Cytoskeletal projections

Hatching

Left-Right Patterning

Metamorphosis

Neurotransmission

Protein Recycling

Drugs by Gene Class

Channels, including ATPases

G Protein Receptors

Kinases

Phosphatases

Small GTPases

Protein Synthesis

Retinoids

Textpresso Small Molecules to Research

Models of Anemia

Environmental toxins