Difference between revisions of "Small Molecules for Xenopus Research"

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(Alphabetical List of Small Molecules With Literature References: Added progesterone .MEF.)
(Alphabetical List of Small Molecules With Literature References)
 
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Line 12: Line 12:
 
*[[11-cis retinal]]
 
*[[11-cis retinal]]
 
*[[18alpha-glycyrretinic acid]]
 
*[[18alpha-glycyrretinic acid]]
 +
*[[2'-deoxyadenosine]]
 +
*[[2-APB]]
 +
*[[2-Deoxyglucose]]
 
*[[3,3,5-triiodothyronine (T3)]]
 
*[[3,3,5-triiodothyronine (T3)]]
 
*[[5HT (seratonin)]]
 
*[[5HT (seratonin)]]
 +
*[[8-Pcpt-2-O-Me-cAMP-AM]]
 
*[[activin]]
 
*[[activin]]
 +
*[[Adenosine, periodate oxidized]]
 
*[[AG1296]]
 
*[[AG1296]]
 
*[[AG1879]]
 
*[[AG1879]]
 
*[[AGN193109]]
 
*[[AGN193109]]
 
*[[alpha-amanitin]]
 
*[[alpha-amanitin]]
 +
*[[Alisertib]]
 
*[[anandamide]]
 
*[[anandamide]]
 +
*[[AP-III-a4]]
 
*[[apelin]]
 
*[[apelin]]
 
*[[aphidicolin]]
 
*[[aphidicolin]]
 +
*[[Aroclor 1254]]
 
*[[AZD1480]]
 
*[[AZD1480]]
 +
*[[Bafilomycin A1]]
 
*[[BAPTA-AM]]
 
*[[BAPTA-AM]]
 +
*[[Barasertib]]
 +
*[[Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)]]
 +
*[[beta-xyloside]]
 +
*[[blebbistatin]]
 
*[[BMS-453]]
 
*[[BMS-453]]
*[[beta-xyloside]]
+
*[[Brefeldin A (BFA)]]
 
*[[bumetanide]]
 
*[[bumetanide]]
 
*[[calcium ionophore]]
 
*[[calcium ionophore]]
 +
*[[canertinib]]
 
*[[CGP54626 ]]
 
*[[CGP54626 ]]
 
*[[Chelerythrine]]
 
*[[Chelerythrine]]
 
*[[chenodeoxycholic acid]]
 
*[[chenodeoxycholic acid]]
 +
*[[chlorpromazine]]
 
*[[chymostatin ]]
 
*[[chymostatin ]]
 
*[[Citral]]
 
*[[Citral]]
 
*[[Colcemide]]
 
*[[Colcemide]]
 
*[[concanamycin]]
 
*[[concanamycin]]
 +
*[[CP-91149]]
 
*[[cycloheximide]]
 
*[[cycloheximide]]
 
*[[cyclopamine]]
 
*[[cyclopamine]]
Line 40: Line 56:
 
*[[Cytochalasin B]]
 
*[[Cytochalasin B]]
 
*[[cytochalasin D]]
 
*[[cytochalasin D]]
 +
*[[D-AP5]]
 +
*[[D-NAME]]
 
*[[Colcemide|Demecolcine]]
 
*[[Colcemide|Demecolcine]]
 
*[[deltamethrin]]
 
*[[deltamethrin]]
Line 46: Line 64:
 
*[[diazepam]]
 
*[[diazepam]]
 
*[[Difopein]]
 
*[[Difopein]]
 +
*[[Diphenyleneiodonium Chloride]]
 +
*[[DMH-1]]
 
*[[Dorsomorphin]]
 
*[[Dorsomorphin]]
 +
*[[DRB]]
 
*[[Ex-527]]
 
*[[Ex-527]]
 
*[[finasteride]]
 
*[[finasteride]]
 +
*[[folic acid]]
 
*[[forskolin]]
 
*[[forskolin]]
 
*[[fusicoccin]]
 
*[[fusicoccin]]
 +
*[[gallein]]
 +
*[[GANT 61]]
 
*[[gentamycin]]
 
*[[gentamycin]]
 +
*[[GSK3-inhibitor IX (BIO)]]
 
*[[GM6001]]
 
*[[GM6001]]
 +
*[[H-89 Dihydrochloride]]
 
*[[heptanol]]
 
*[[heptanol]]
 
*[[herbimycin A]]
 
*[[herbimycin A]]
 
*[[Hydroxyurea]]
 
*[[Hydroxyurea]]
 
*[[IBMX]]
 
*[[IBMX]]
 +
*[[Iodoacetic acid]]
 
*[[jasplakinolide]]
 
*[[jasplakinolide]]
 +
*[[6-B345TTQ]]
 +
*[[Ketamine]]
 
*[[KT 5720]]
 
*[[KT 5720]]
 +
*[[L-NAME]]
 
*[[lansoprazole]]
 
*[[lansoprazole]]
 +
*[[latrunculin A]]
 
*[[latrunculin B]]
 
*[[latrunculin B]]
*[[LDN193187]]
+
*[[LDN-193189]]
 +
*[[Leflunomide]]
 +
*[[leucovorin]]
 
*[[LiCl]]
 
*[[LiCl]]
 +
*[[Lovastatin]]
 
*[[LY294002]]
 
*[[LY294002]]
 +
*[[m-3M3FBS]]
 +
*[[methotrexate (MTX)]]
 +
*[[metronidazole]]
 
*[[Mg132]]
 
*[[Mg132]]
 +
*[[MK-2206]]
 
*[[MMP-2 inhibitor II]]
 
*[[MMP-2 inhibitor II]]
 +
*[[MS-275]]
 +
*[[Mubritinib]]
 
*[[nicorandil]]
 
*[[nicorandil]]
 
*[[Nicotinamide]]
 
*[[Nicotinamide]]
 +
*[[Nicotinic acid]]
 
*[[nifedipine]]
 
*[[nifedipine]]
 
*[[nocodazole]]
 
*[[nocodazole]]
Line 75: Line 116:
 
*[[olomoucine]]
 
*[[olomoucine]]
 
*[[ouabain]]
 
*[[ouabain]]
 +
*[[Olygomycin]]
 
*[[PD173074]]
 
*[[PD173074]]
 
*[[PD-407824]]
 
*[[PD-407824]]
Line 86: Line 128:
 
*[[Progesterone]]
 
*[[Progesterone]]
 
*[[propylthiouracil]]
 
*[[propylthiouracil]]
 +
*[[pyrimethamine]]
 
*[[quinpirole]]
 
*[[quinpirole]]
 +
*[[rac1 inhibitor]]
 
*[[rapamycin]]
 
*[[rapamycin]]
 
*[[retinoic acid]]
 
*[[retinoic acid]]
 
*[[Retinol]]
 
*[[Retinol]]
 +
*[[RO-3306]]
 
*[[RS67333]]
 
*[[RS67333]]
 
*[[RU486]]
 
*[[RU486]]
 +
*[[SAHA]]
 
*[[SB 203580]]
 
*[[SB 203580]]
 +
*[[SB431542]]
 +
*[[SB 505124]]
 
*[[SCH28080]]
 
*[[SCH28080]]
 +
*[[SNAP]]
 
*[[sodium nitroprusside]]
 
*[[sodium nitroprusside]]
 +
*[[sodium perchlorate]]
 
*[[SP600125 ]]
 
*[[SP600125 ]]
 
*[[SU5402]]
 
*[[SU5402]]
Line 103: Line 153:
 
*[[thyroxine (T4)]]
 
*[[thyroxine (T4)]]
 
*[[Torin 2]]
 
*[[Torin 2]]
 +
*[[Trichostatin A]]
 +
*[[trimetrexate]]
 +
*[[Triptolide]]
 
*[[TTNPB]]
 
*[[TTNPB]]
 +
*[[Tubercidin]]
 
*[[tunicamycin]]
 
*[[tunicamycin]]
 
*[[Tyrphostin AG 1478]]
 
*[[Tyrphostin AG 1478]]
 +
*[[U73122]]
 
*[[Y27632]]
 
*[[Y27632]]
 
*[[ZM 447439]]
 
*[[ZM 447439]]
Line 118: Line 173:
 
*[[beclomethasone]]
 
*[[beclomethasone]]
 
*[[Butyrate]]
 
*[[Butyrate]]
 +
*[[calcicludine]]
 
*[[Calyculin A]]
 
*[[Calyculin A]]
 
*[[celastrol]]
 
*[[celastrol]]
Line 128: Line 184:
 
*[[diclofenac]]
 
*[[diclofenac]]
 
*[[etoposide]]
 
*[[etoposide]]
 +
*[[IWR1]]
 
*[[GW843682X]]
 
*[[GW843682X]]
 
*[[leptomycin B]]
 
*[[leptomycin B]]
 
*[[LY320135]]
 
*[[LY320135]]
*[[Methotrexate (MTX)]]
 
 
*[[methylcellulose (MC)]]
 
*[[methylcellulose (MC)]]
 
*[[methimazole]]
 
*[[methimazole]]
Line 138: Line 194:
 
*[[nicardipine]]
 
*[[nicardipine]]
 
*[[Nu6102]]
 
*[[Nu6102]]
*[[PTU|propylthiouracil(PTU) inhibits thyroxine]]
+
*[[phenylthiourea|phenylthiourea (PTU)]]
*[[PTU|phenylthiouracil(PTU inhibits melanophore formation]]
 
 
*[[purmorphamine]]
 
*[[purmorphamine]]
 
*[[Pyrazoleanthrone]]
 
*[[Pyrazoleanthrone]]
Line 145: Line 200:
 
*[[RHC80267]]
 
*[[RHC80267]]
 
*[[RL-3]]
 
*[[RL-3]]
 +
*[[SAG]]
 
*[[SB-431542]]
 
*[[SB-431542]]
*[[SB505124]]
 
 
*[[TG003]]
 
*[[TG003]]
 
*[[Thapsigargin]]
 
*[[Thapsigargin]]
*[[Trichostain A]]
 
 
*[[U0126]]
 
*[[U0126]]
*[[U73122]]
 
 
*[[ursodeoxycholic acid]]
 
*[[ursodeoxycholic acid]]
 
*[[Echinomycin]]
 
*[[Echinomycin]]
 
*[[Gö 6983]]
 
*[[Gö 6983]]
 
*[[phenylhydrazine]]
 
*[[phenylhydrazine]]
 +
*[[ω-conotoxin–GVIA]]
 +
*[[flunarizine]]
 +
*[[tetrodotoxin]]
 +
*[[veratridine]]
 +
*[[NBI-27914]]
  
 
==Small Molecules Affecting Pathways==
 
==Small Molecules Affecting Pathways==
Line 164: Line 222:
 
===CDK/Cyclins===
 
===CDK/Cyclins===
 
*[[olomoucine]]
 
*[[olomoucine]]
 +
*[[RO-3306]]
  
 
===ERK/MAPK===
 
===ERK/MAPK===
Line 195: Line 254:
 
*[[cyclopamine]]
 
*[[cyclopamine]]
 
*[[purmorphamine]]
 
*[[purmorphamine]]
 +
*[[Vismodegib]]
  
 
===TGF-beta/BMP===
 
===TGF-beta/BMP===
Line 205: Line 265:
 
===Wnt===
 
===Wnt===
 
*[[LiCl]]
 
*[[LiCl]]
 +
*[[GSK3-inhibitor IX (BIO)]]
 +
*[[IWR1]]
  
 
===Epigenetics===
 
===Epigenetics===
Line 247: Line 309:
 
*[[cytochalasin D]]
 
*[[cytochalasin D]]
 
*[[Colcemide]]
 
*[[Colcemide]]
 +
*[[Colchicine]]
 
*[[jasplakinolide]] is an activator
 
*[[jasplakinolide]] is an activator
 
*[[latrunculin B]]
 
*[[latrunculin B]]
Line 266: Line 329:
 
===DNA Synthesis===
 
===DNA Synthesis===
 
*[[Calyculin A]]
 
*[[Calyculin A]]
 +
 +
===DNA mutagenic compounds===
 +
*[[ENU or N-nitroso-N-ethylurea]] 100mM Sigma N3385
 +
  
 
===Growth Cone, Filopodia, and other Cytoskeletal projections===
 
===Growth Cone, Filopodia, and other Cytoskeletal projections===

Latest revision as of 13:29, 13 August 2019

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Important small molecule references

Alphabetical List of Small Molecules With Literature References

The Following are in need of standardization and curation

Small Molecules Affecting Pathways

cAMP

CDK/Cyclins

ERK/MAPK

Folic Acid

JAK/STAT

JNK

Nitric Oxide

PDGF

Retinoic Acid

Shh

TGF-beta/BMP

Thyroid Signaling

Wnt

Epigenetics

Protease Inhibitors

Small Molecules affecting Biological Functions & Processes

Angiogenesis

Apoptosis

Autophagy

Calcium Signaling

Circadian Rhythm

Cytoskeletal Inhibitors

Cell Cycle, including mitosis

Cilia

DNA Damage/Repair

DNA Synthesis

DNA mutagenic compounds


Growth Cone, Filopodia, and other Cytoskeletal projections

Hatching

Left-Right Patterning

Metamorphosis

Neurotransmission

Protein Recycling

Drugs by Gene Class

Channels, including ATPases

G Protein Receptors

Kinases

Phosphatases

Small GTPases

Protein Synthesis

Retinoids

Textpresso Small Molecules to Research

Models of Anemia