AZD1480 and File:Azd1480.gif: Difference between pages

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==Description==
Inhibits the Jak Stat pathway. AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.
[[File:azd1480.gif|frame|right|Structure of AZD1479, photo from Selleck Chemical]]


**Genes Affected
**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=483749 jak1]
**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=483711 jak2]
==Suppliers==
*[https://pubchem.ncbi.nlm.nih.gov/compound/16659841 PubChem]
*[http://www.selleckchem.com/products/azd1480.html Selleck Chemicals]
*[http://www.scbt.com/datasheet-364735-azd1480.html Santa Cruz ]
==Usage Notes==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50713 Hyakutake et al., 2015]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42239 Bergmann et al., 2010]
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Revision as of 07:17, 28 May 2015