AZD1480: Difference between revisions

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==Description==
==Description==
Inhibits the Jak Stat pathway
Inhibits the Jak Stat pathway. AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.
[[File:azd1480.gif]]


**Genes Affected
**Genes Affected
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==Suppliers==
==Suppliers==
Selleck Chemicals
[http://www.selleckchem.com/products/azd1480.html Selleck Chemicals]
Santa Cruz  
[http://www.scbt.com/datasheet-364735-azd1480.html Santa Cruz ]
==Usage Notes==
==Usage Notes==


==References==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50713 ____ et al., 2xxxx]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50713 Hyakutake et al., 2015]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42239 ____ et al., 2xxxx]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42239 Bergmann et al., 2010]

Revision as of 07:18, 28 May 2015

Description

Inhibits the Jak Stat pathway. AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.

Suppliers

Selleck Chemicals Santa Cruz

Usage Notes

References