Concanamycin: Difference between revisions
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imported>Kevin (Created page with "==Description== V-ATPase inhibitor, see fusicoccin for an activator. "Cytotoxic. Inhibits acidification of organelles and perforin-mediated cytotoxicity." **-Sigma Descri...") |
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*[http://www.xenbase.org/literature/article.do?method=display&articleId=41876 Jansen 2010] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=41876 Jansen 2010] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=42120 Tseng 2010] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=42120 Tseng 2010] | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | |||
Revision as of 07:52, 1 June 2015
Description
V-ATPase inhibitor, see fusicoccin for an activator.
"Cytotoxic. Inhibits acidification of organelles and perforin-mediated cytotoxicity."
- -Sigma Description
"Specific inhibitor of V-type (vacuolar) H+-ATPase that displays > 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines."
- -Tocris Description
Suppliers
Usage Notes
2M
References
>11 Xenbase articles contain a reference to concanamycin according to textpresso including these: