Retinoic acid: Difference between revisions

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==Description==
==Description==
"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."
*-Sigma Product Description
[[File:RetinoicAcid.png|frame|right|Retinoic Acid structure, photo from Sigma-Aldrich]]
[[File:RetinoicAcid.png|frame|right|Retinoic Acid structure, photo from Sigma-Aldrich]]


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==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/compound/444795]
*[https://pubchem.ncbi.nlm.nih.gov/compound/444795 Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=21398 Drysdale et al., 1991]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=21398 Drysdale et al., 1991]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50590 Nagy et al., 2015]


>1484 Xenbase articles contain a reference to Retinoic Acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>1484 Xenbase articles contain a reference to Retinoic Acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 17:00, 7 March 2016

Description

"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."

  • -Sigma Product Description
Retinoic Acid structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

References

>1484 Xenbase articles contain a reference to Retinoic Acid according to textpresso