XB-FEAT-1013836

inppl1a

This is the community wiki page for the gene inppl1a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenlcature changes

09FEB2023

Xenopus gene name for XB-GENEPAGE-1013836 changed from inppl1, inositol polyphosphate phosphatase-like 1 to inppl1a, inositol polyphosphate phosphatase-like 1a

this follows examination of INPPL1 genes in vertebrates.

Most vertebrates groups have two INPPL1 genes but mammals have lost one of them (INPPL1B).

we will creat a new genepage on Xenbase for inppl1b to include Xtr GeneID: 100496685 and Xla.L GeneID: 108698315 . There is no inppl1b.S gene.

synteny patterns for INPPL1A/B in Vertebrates

Source: DAVID WEBB @REFSEQ NCBI

INPPL1 (aka INPPL1A) HUMAN: ANAPC15< FOLR3> FOLR1> FOLR2> INPPL1> PHOX2A< CLPB< PDE2A<

MonDom

ANAPC15<folr3> folr1> folr2> INPPL1> PHOX2A< CLPB< LOC<

echidna XP_038620978.1

LAMTOR1< ANAPC15< LOC< LOC> folr> INPPL1> PHOX2A< CLPB< LOC>

Pheasant XP_031456985

LAMTOR1< LOC> ANAPC15< folr> INPPL1> PHOX2A< CLPB<

GALLUS XM_040656636.1[PARTIAL], emu XP_025978297.1 //inppl1>//

chelonia XP_037769744.1

ANAPC15<folr3> folr1> folr2> INPPL1> PHOX2A< CLPB< STARD10>

podarcis XP_028581607.1

LAMTOR1< LOC> ANAPC15< folr> INPPL1> PHOX2A< CLPB< STARD10>

Xtr XP_031753288.1

LAMTOR1< SFRPX> tomt< FOLR1> INPPL1> PHOX2A< CLPB<

rana XP_040189969.1

INPPL1> PHOX2A< CLPB<

microcacaelia XP_030055838.1

LAMTOR1< LOC> folr> INPPL1> PHOX2A< CLPB< STARD10>

D. rerio NP_001034893.1

SIK3/SIDT2< INPPL1A> PHOX2A< CLPB< LOC< folr< ANAPC15>

INPPL1B

Human, koala

PDZD11> RAB41< ARR3< P2RY4> AWAT1< DGAT2L6< IGBP1<

platypus

PDZD11> stard10-like< RAB41< ARR3< awat1< dgat2l6< IGBP1<

Gallus XP_015133832.2

PDZD11> stard10-like< RAB41< ARR3< "INNPL1"> P2RY4> AWAT1/dgat2< IGBP1<

Pheasant XP_031449847.1, emu XP_025951802.1

PDZD11> stard10-like< RAB41< ARR3< inppl1-like> P2RY4> dgat2< IGBP1<

croc XP_019391783.1[misnamed INPPL1], chelonia XP_043377770.1

PDZD11> stard10-like< RAB41< ARR3< inppl1-like> P2RY4> dgat2< IGBP1<

Xtr XP_031746720.1

stard10-like< RAB41< ARR3< inppl1-like> P2RY4> DGAT2L6< IGBP1<

Rana XP_040190387.1 ARR3< innpl1-like> p2ry4> loc< PDZD11<

microcacaelia XP_030065653.1 RAB41< inppl1-like> IGBP1<

protoperus XP_043913229.1

PDZD11> stard10-like< rab41< ARR3< inppl1-like> p2ry4< p2ry4>

D.rerio INPPL1B NP_001034224.2

ARR3B< INPPL1B > P2RY4> SOX3>