XB-FEAT-12565069

From XenWiki
Revision as of 09:54, 21 May 2019 by imported>Xenbase (Created page with "=ptprn2= =nomenclature changes= 05.13.19 Human name has changed for Entrez Gene: 5779. From protein tyrosine phosphatase, receptor type N2 to protein tyrosine phosphatase rec...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

ptprn2

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 5779. From protein tyrosine phosphatase, receptor type N2 to protein tyrosine phosphatase receptor type N2

Summary from NCBI for humanPTPRN2

This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]