BMS-453

From XenWiki
Revision as of 14:53, 23 June 2016 by imported>Mfisher
Jump to navigation Jump to search

Description

Synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.

Bms 453 structure, photo from Tocris

Alternative Name

BMS 189453

Chemical Name

4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid

Pubchem ID

CID:9875424

Suppliers

References