RU486

Description

Synonym: Mifepristone "Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME."

• -Pubchem Description

RU486 structure, photo from pubchem

Genes Affected

• creb1

Suppliers

• Sigma

References

• Pubchem
• Lutz et al., 1999
• Schreiber 2011

>43 Xenbase articles contain a reference to RU486 according to textpresso

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