XB-FEAT-6456827 and BAPTA-AM: Difference between pages

Latest revision as of 13:28, 2 June 2015

Description

Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.

Structure of BAPTA-AM, photo from Sigma-Aldrich

- Genes Affected
- kcnh2
- kcna5
- kcna3

Suppliers

Usage Notes

.4uM in .1x NAM

References

>762 Xenbase articles contain a reference to BAPTA-AM according to textpresso

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@@ Line 1: / Line 1: @@
-=rusc1=
+==Description==
-This is the community wiki page for the gene ''rusc1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
+Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.
+[[File:BAPTAAM.png|frame|right|Structure of BAPTA-AM, photo from Sigma-Aldrich]]
+**Genes Affected
+**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=983103 kcnh2]
+**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=6037400 kcna5]
+**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=991577 kcna3]
+==Suppliers==
+*[https://www.lifetechnologies.com/order/catalog/product/B1205 Life Technologies B1205]
+*[http://www.sigmaaldrich.com/catalog/product/sigma/a1076?lang=en&region=US Sigma A1076]
+*[http://www.tocris.com/dispprod.php?ItemId=5296#.VWcXP9LBzRY Tocris 2787]
+*[http://www.scbt.com/datasheet-202488-bapta-am.html Santa Cruz sc-202488]
+==Usage Notes==
+.4uM in .1x NAM
+==References==
+*[https://pubchem.ncbi.nlm.nih.gov/compound/2293 PubChem]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=4661 Leclerc et al., 2003]
+>762 Xenbase articles contain a reference to BAPTA-AM according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
+*
+*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]