From XenWiki
(Difference between pages)
imported>Kevin |
imported>Mardi |
| Line 1: |
Line 1: |
| ==Description==
| |
| Activator of adenylyl cyclase.
| |
|
| |
|
| Marketed as a dietary supplement/alternative medication.
| |
|
| |
| "Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase."
| |
| **-Sigma product description
| |
|
| |
| [[File:forskolin.png|frame|right|forskolin structure, photo from Sigma-Aldrich]]
| |
|
| |
| ==Genes Affected==
| |
| *[http://www.xenbase.org/gene/searchGene.do?method=search&searchIn=0&searchValue=adenylate%20cyclase&searchType=0 adenylyl cyclase]
| |
|
| |
| ==Suppliers==
| |
| *[http://www.sigmaaldrich.com/catalog/product/sigma/f6886?lang=en®ion=US Sigma F6886]
| |
| *[http://www.scbt.com/datasheet-3562-forskolin.html Santa Cruz sc-3562]
| |
| *[http://www.tocris.com/dispprod.php?ItemId=2337#.VWeG9tLBzRY Tocris 1099]
| |
|
| |
| ==Usage Notes==
| |
| 50uM
| |
|
| |
| ==References==
| |
| *[https://pubchem.ncbi.nlm.nih.gov/compound/47936 PubChem]
| |
| *[http://www.xenbase.org/literature/article.do?method=display&articleId=11986 Kim et al., 1999]
| |
|
| |
| >786 Xenbase articles contain a reference to Forskolin according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
| |
| *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
| |
Revision as of 14:52, 30 November 2017
