XB-FEAT-5768035: Difference between revisions
imported>KABurns (→ocm.2) |
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= | =''ocm4.3''= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''ocm4.3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
This gene was renamed to ocm4.3 | This gene was renamed from ''ocm.2'' to ''ocm4.3'' on 7/1/2019 by Xenbase curators (KAB) | ||
This gene is part of the ocm locus which has 3 ancestral genes | This gene is part of the 'ocm' locus which has 3 ancestral genes. | ||
The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1 Note that | Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. | ||
KAB unilaterally renamed this more ancestral gene as 'ocm4' to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human. | |||
The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1 | |||
Note that Xenopus massively duplicated the OCM4 paralogue. | |||
This gene should not be renamed unless instructed by HGNC | This gene should not be renamed unless instructed by HGNC | ||
=synteny maps= | |||
Chicken: rsph10b> ccz1< loc#> ocm1< ocm4< ocm3< Loc< lmtk2> | |||
HUMAN : RNF216< ZNF815P> OCM> RN7SL556P< CCZ1> LOC< LOC> | |||
Xla.S ch9: ''ocm3> ocm4.1> ocm4.2> ocm4.3 > ocm4.5> ocm4.6> ocm1> ccz1b> rsph10b<'' | |||
Xla.L ch9_10: ''ocm4.1.L > ocm4.2.L > ocm4.3.L > ocm4.7.L > ocm4.8.L > ocm4.9.L > ocm4.10. L> ocm4.4.L > ocm4.5.L> ocm4.6> ocm1.L > ccz1.L> eif2ak1.L'' | |||
Xtr: ''rsph10b> ccz1< ocm1< ocm4.6< loc#< ocm4.5< ocm4.4<. ocm4.3<. ocm4.2< ocm4.1<'' | |||
Latest revision as of 11:48, 6 June 2023
ocm4.3
This is the community wiki page for the gene ocm4.3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
This gene was renamed from ocm.2 to ocm4.3 on 7/1/2019 by Xenbase curators (KAB)
This gene is part of the 'ocm' locus which has 3 ancestral genes.
Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2.
KAB unilaterally renamed this more ancestral gene as 'ocm4' to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.
The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1
Note that Xenopus massively duplicated the OCM4 paralogue.
This gene should not be renamed unless instructed by HGNC
synteny maps
Chicken: rsph10b> ccz1< loc#> ocm1< ocm4< ocm3< Loc< lmtk2>
HUMAN : RNF216< ZNF815P> OCM> RN7SL556P< CCZ1> LOC< LOC>
Xla.S ch9: ocm3> ocm4.1> ocm4.2> ocm4.3 > ocm4.5> ocm4.6> ocm1> ccz1b> rsph10b<
Xla.L ch9_10: ocm4.1.L > ocm4.2.L > ocm4.3.L > ocm4.7.L > ocm4.8.L > ocm4.9.L > ocm4.10. L> ocm4.4.L > ocm4.5.L> ocm4.6> ocm1.L > ccz1.L> eif2ak1.L
Xtr: rsph10b> ccz1< ocm1< ocm4.6< loc#< ocm4.5< ocm4.4<. ocm4.3<. ocm4.2< ocm4.1<