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| ==Description==
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| Synonym: 4-Amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, AG 1879
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| "PP2 is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2."
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| *-Sigma Product Description
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| [[File:PP2.png|frame|right|PP2 structure, photo from Sigma-Aldrich]]
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| ==Genes Affected==
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| *[http://www.xenbase.org/gene/showgene.do?method=display&geneId=489819 src]
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| ==Suppliers==
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| *[http://www.emdmillipore.com/US/en/product/PP2---CAS-172889-27-9---Calbiochem,EMD_BIO-529573?bd=1 Calbiochem is now EMD Millipore]
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| *[http://www.sigmaaldrich.com/catalog/product/sigma/p0042?lang=en®ion=US Sigma]
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| ==Usage Notes==
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| 1uM in cell culture media, up to 10mM in certain applications
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| ==References==
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=1490 Robles et al., 2005]
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| *[http://www.xenbase.org/literature/article.do?method=display&articleId=9003 Browaeys-Poly et al. 2001]
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| >18 Xenbase articles contain a reference to PP2 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
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| *
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| *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
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Revision as of 14:48, 8 August 2016
