PP2: Difference between revisions

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(Created page with "==Description== Synonym: 4-Amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, AG 1879 "PP2 is...")
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Revision as of 10:51, 2 June 2015

Description

Synonym: 4-Amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, AG 1879

"PP2 is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2."

  • -Sigma Product Description
PP2 structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

1uM in cell culture media, up to 10mM in certain applications

References

>18 Xenbase articles contain a reference to PP2 according to textpresso