XB-FEAT-5802730

XB5802730 provisional rab10l

This is the community wiki page for the gene XB5802730 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature updates

02.27.2-21 the name of this newly annotated gene is currently being reviewed by David Webb at NCBI/RefSeq.

based on synteny and sequence identity, it is suggested to be 'Ras-related protein Rab-10-like' with gene symbol rab10l in Xenopus.

Note: the gene seems to be lost in mammals, and Zebrafish, but is present in chicken (Gene ID:421099)

syntenty notes:

non-mammalian osteichthyes in general: CCDC178>...KLHL14>...RAB10L>...GAREM1>...MEP1B<

mammals (in general) (lost): CCDC178>...KLHL14>... ...GAREM1>...MEP1B<

Frogs and reedfish: CCDC178>...KLHL14>...RAB10L>...GAREM1>...MCM3>...MEP1B<

D.rerio: I can't find RAB10L in D. rerio: CCDC178>...KLHL14>...ABCD4>...OBSCNB>

skate (also missing/lost): CCDC178>...KLHL14>... ...GAREM1>...LRRC6>...KCNQ3>

most gnathostomes have paralogous gene pair: KIF3C<...RAB10>...GAREM2>...HADHA<...HADHB>

lamprey has just RAB10L (GeneID:116942554) and GAREM (GeneID:116942506) genes so RAB10-GAREM duplication may have happened in gnathostomes

MTFR2>...DNMT3A<...KLHL14>...RAB10L>...GAREM>...ADGRF<...ADGRF<