Trimetrexate and D-AP5: Difference between pages

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==Description==
==Description==
Nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase
D-AP5 is the D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE).


[[File:trimetrexate.png|frame|right| structure, image from PubChem]]
[[File:Screen Shot 2017-12-22 at 10.47.54 AM.pngframe|right|? structure, image from PubChem]]


==Alternative names==
==Alternative names==
*Trimetrexato
*APV
*Trimetrexatum
*2-APV
*Trimetrexate Hydrate


==Usage Notes==
==Usage Notes==
==References==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=53082 Balashova et al 2017]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=324]
*[https://pubchem.ncbi.nlm.nih.gov/compound/126941 NCBI PubChem CID:5583]
*[https://pubchem.ncbi.nlm.nih.gov/compound/126941 NCBI PubChem CID:135342]


> 2 Xenbase articles contain a reference to Methotrexate according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*> 220 Xenbase articles contain a reference to D-AP5 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home
Page]]
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Revision as of 09:51, 22 December 2017

Description

D-AP5 is the D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE).

? structure, image from PubChem
? structure, image from PubChem

Alternative names

  • APV
  • 2-APV

Usage Notes

References