BMS-453: Difference between revisions
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==Chemical Name== | ==Chemical Name== | ||
4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid | 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid | ||
==Pubchem ID== | ==Pubchem ID== | ||
CID:9875424 | *[https://pubchem.ncbi.nlm.nih.gov/compound/9875424#section=Related-Records| CID:9875424] | ||
==Suppliers== | ==Suppliers== | ||
[https://www.tocris.com/dispprod.php?ItemId=222005#.V2xIRfkrKM8 Tocris] | |||
==References== | ==References== | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=51800| ''Using frogs faces to dissect the mechanisms underlying human orofacial defects''. Dickinson AJ. Semin Cell Dev Biol. March 1, 2016; 51 54-63.] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=51800| ''Using frogs faces to dissect the mechanisms underlying human orofacial defects''. Dickinson AJ. Semin Cell Dev Biol. March 1, 2016; 51 54-63.] | ||
Revision as of 14:54, 23 June 2016
Description
Synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.
Alternative Name
BMS 189453
Chemical Name
4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid