XB-FEAT-6257460: Difference between revisions
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Human symbol has changed for genepage ID: 6257460 From transient receptor potential cation channel, subfamily M, member 2 like to tripartite motif containing 26 | Human symbol has changed for genepage ID: 6257460 From transient receptor potential cation channel, subfamily M, member 2 like to tripartite motif containing 26 | ||
1MAY2023 | |||
Synteny (below) does not support the orthology between Xenopus and human trim26/TRIM26, and NCBI orthology analysis also does not identify Xtrop Gene ID:100491139 as an ortholog of TRIM26. Thus we conclude that this gene has been misannotated and incorrectly named trim26. | |||
XB Action: removed the vertebrate orthologs for TRIM26 from this gene page, and renamed these genes ''trpm2l, transient receptor potential cation channel, subfamily M, member 2 like'' | |||
Synteny as of April 29th, 2023 | |||
Human: TRIM 10 ... TRIM15 ...PAIP1P1 ... '''TRIM26''' ... TRIM26BP ... HCG17 | |||
XTR.chr2: ilk ... tpp1 ... ''''trim26'''' ... zscan2 | |||
Xla.chr2L: dynp1 ... rrp8.L ... mgc822989 ...tpp1 ...tif-if2 ...''''trim26'''' .. zfp391 | |||
=summary for human TRIM26 from NCBI= | =summary for human TRIM26 from NCBI= | ||
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011] | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011] | ||
Revision as of 08:57, 1 May 2023
trim26
This is the community wiki page for the gene trim26 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
06.30.2020
Human symbol has changed for genepage ID: 6257460 From trpm2l to trim26
Human symbol has changed for genepage ID: 6257460 From transient receptor potential cation channel, subfamily M, member 2 like to tripartite motif containing 26
1MAY2023
Synteny (below) does not support the orthology between Xenopus and human trim26/TRIM26, and NCBI orthology analysis also does not identify Xtrop Gene ID:100491139 as an ortholog of TRIM26. Thus we conclude that this gene has been misannotated and incorrectly named trim26.
XB Action: removed the vertebrate orthologs for TRIM26 from this gene page, and renamed these genes trpm2l, transient receptor potential cation channel, subfamily M, member 2 like
Synteny as of April 29th, 2023
Human: TRIM 10 ... TRIM15 ...PAIP1P1 ... TRIM26 ... TRIM26BP ... HCG17 XTR.chr2: ilk ... tpp1 ... 'trim26' ... zscan2 Xla.chr2L: dynp1 ... rrp8.L ... mgc822989 ...tpp1 ...tif-if2 ...'trim26' .. zfp391
summary for human TRIM26 from NCBI
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]