XB-FEAT-6257460: Difference between revisions
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1MAY2023 | 1MAY2023 | ||
Synteny (below) does not support the orthology between ''Xenopus'' and human trim26/TRIM26, and NCBI orthology analysis also does not identify Xtrop Gene ID:100491139 as an ortholog of TRIM26. Thus we conclude that | Synteny (below) does not support the orthology between ''Xenopus'' GeneID:100491139 and GeneID:108707608 and human trim26/TRIM26, and NCBI orthology analysis also does not identify Xtrop Gene ID:100491139 as an ortholog of TRIM26. Thus we conclude that these genes has been misannotated and incorrectly named ''trim26''. | ||
Q:IS THIS GENE THE ORTHOLOG OF TRPM2? | Q:IS THIS GENE THE ORTHOLOG OF TRPM2? | ||
A: No, Xtrop Gene ID: 100124999 is identified by | A: No, Xtrop Gene ID: 100124999 is identified by NBCI as the true ortholog of TRPM2, although synteny is not conserved. | ||
XB Actions: | XB Actions: | ||
1) removed the vertebrate orthologs for TRIM26 from this gene page | 1) removed the vertebrate orthologs for TRIM26 from this gene page | ||
2) renamed these genes ''trpm2l, transient receptor potential cation channel, subfamily M, member 2 like'' | 2) renamed these genes ''trpm2l, transient receptor potential cation channel, subfamily M, member 2 like'' | ||
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Human: TRIM 10 TRIM15 PAIP1P1 '''TRIM26''' TRIM26BP HCG17 | Human: TRIM 10 TRIM15 PAIP1P1 '''TRIM26''' TRIM26BP HCG17 | ||
XTR.chr2: ilk tpp1 ''''trim26'''' zscan2 | XTR.chr2: ilk tpp1 ''''trim26 [GeneID:100491139]'''' zscan2 | ||
Xla.chr2L: dynp1 rrp8.L mgc822989 tpp1 tif-if2 ''''trim26'''' zfp391 | Xla.chr2L: dynp1 rrp8.L mgc822989 tpp1 tif-if2 ''''trim26 [GeneID:108707608] '''' zfp391 | ||
Revision as of 09:14, 1 May 2023
trim26
This is the community wiki page for the gene trim26 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
06.30.2020
Human symbol has changed for genepage ID: 6257460 From trpm2l to trim26
Human symbol has changed for genepage ID: 6257460 From transient receptor potential cation channel, subfamily M, member 2 like to tripartite motif containing 26
1MAY2023
Synteny (below) does not support the orthology between Xenopus GeneID:100491139 and GeneID:108707608 and human trim26/TRIM26, and NCBI orthology analysis also does not identify Xtrop Gene ID:100491139 as an ortholog of TRIM26. Thus we conclude that these genes has been misannotated and incorrectly named trim26.
Q:IS THIS GENE THE ORTHOLOG OF TRPM2? A: No, Xtrop Gene ID: 100124999 is identified by NBCI as the true ortholog of TRPM2, although synteny is not conserved.
XB Actions:
1) removed the vertebrate orthologs for TRIM26 from this gene page
2) renamed these genes trpm2l, transient receptor potential cation channel, subfamily M, member 2 like
Synteny as of April 29th, 2023
Human: TRIM 10 TRIM15 PAIP1P1 TRIM26 TRIM26BP HCG17
XTR.chr2: ilk tpp1 'trim26 [GeneID:100491139]' zscan2
Xla.chr2L: dynp1 rrp8.L mgc822989 tpp1 tif-if2 'trim26 [GeneID:108707608] ' zfp391
Human chr21: ICOSLG< DNMT3L AIRE PFKL> CFAP410. TRPM2 LRRC3 TSPEAR UGE2G2< SUMO3 PTTG1IP< ITGB2< SLX9>
Xtrop.Chr9: col5a2> col3a1<. gulp1< cfap410< trmp2>'Bold text' pth2r> pikfyve< c9h2orf80>