File:Ph3.jpg and Forskolin: Difference between pages

Latest revision as of 12:48, 8 January 2018

Description

Activator of adenylyl cyclase.

Marketed as a dietary supplement/alternative medication.

"Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase."

- -Sigma product description

forskolin structure, photo from Sigma-Aldrich

Genes Affected

adenylyl cyclase

Suppliers

Usage Notes

50uM

References

>786 Xenbase articles contain a reference to Forskolin according to textpresso

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	17:15, 5 April 2022		911 × 892 (152 KB)	Maintenance script (talk \| contribs)	== Summary == Importing file

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Histone H3, phosphorylated - h3f3a - mitotic cells - from upstate

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Author	Yves Nicodem
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Horizontal resolution	72 dpi
Vertical resolution	72 dpi
Data arrangement	chunky format
Software used	Adobe Photoshop CS3 Macintosh
File change date and time	17:04, 15 April 2011
Color space	Uncalibrated
Image width	911 px
Image height	892 px
Date and time of digitizing	11:04, 15 April 2011
Date metadata was last modified	11:04, 15 April 2011

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+==Description==
+Activator of adenylyl cyclase.
+Marketed as a dietary supplement/alternative medication.
+"Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase."
+**-Sigma product description
+[[File:forskolin.png|frame|right|forskolin structure, photo from Sigma-Aldrich]]
+==Genes Affected==
+*[http://www.xenbase.org/gene/searchGene.do?method=search&searchIn=0&searchValue=adenylate%20cyclase&searchType=0 adenylyl cyclase]
+==Suppliers==
+*[http://www.sigmaaldrich.com/catalog/product/sigma/f6886?lang=en&region=US Sigma F6886]
+*[http://www.scbt.com/datasheet-3562-forskolin.html Santa Cruz sc-3562]
+*[http://www.tocris.com/dispprod.php?ItemId=2337#.VWeG9tLBzRY Tocris 1099]
+==Usage Notes==
+uM
+==References==
+*[https://pubchem.ncbi.nlm.nih.gov/compound/47936 PubChem]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=11986 Kim et al., 1999]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=50905 Begacem et al., 2015]
+>786 Xenbase articles contain a reference to Forskolin according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
+*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]