XB-FEAT-868116: Difference between revisions
imported>Xenbase gene generator No edit summary |
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= | =tle5= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''tle5'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
05.13.19 | |||
Human name has changed for Entrez Gene: 166. From amino-terminal enhancer of split to TLE family member 5, transcriptional modulator | |||
Human symbol has changed for genepage ID: 868116 From aes to TLE5 | |||
Human symbol has changed for Entrez Gene: 166. From AES to TLE5 | |||
Zebrafish symbol has changed for Entrez Gene: 393395. From aes to tle5 | |||
Mouse symbol has changed for Entrez Gene: 14797. From Aes to Tle5 | |||
=Summary from NCBI for human TLE5 = | |||
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |||
Latest revision as of 06:11, 15 May 2019
tle5
This is the community wiki page for the gene tle5 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
05.13.19
Human name has changed for Entrez Gene: 166. From amino-terminal enhancer of split to TLE family member 5, transcriptional modulator
Human symbol has changed for genepage ID: 868116 From aes to TLE5
Human symbol has changed for Entrez Gene: 166. From AES to TLE5
Zebrafish symbol has changed for Entrez Gene: 393395. From aes to tle5
Mouse symbol has changed for Entrez Gene: 14797. From Aes to Tle5
Summary from NCBI for human TLE5
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]