XB-FEAT-876556: Difference between revisions

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=background to nomenclature chanhges=
=background to nomenclature changes=


NCBI refSeq nd HGNC communicated the following....
05May2023
 
NCBI refSeq and HGNC communicated the following....


...there seems to be some confusion in the Xenbase "nif" record XB-GENEPAGE-876556: there is an unrelated gene that has also been published as "XNIF" (PMID 15294863/AY280863) which from BLATing the sequence maps to chr 6 and appears to be ''ctdspl'', and so rather confusingly the CTDSPL synonym is listed in the real "nif" gene record. And PMID 2307698 which talks about the unrelated "NIF-1" and "NIF-2" has crept into the "nif" record and I think it should be removed.
...there seems to be some confusion in the Xenbase "nif" record XB-GENEPAGE-876556: there is an unrelated gene that has also been published as "XNIF" (PMID 15294863/AY280863) which from BLATing the sequence maps to chr 6 and appears to be ''ctdspl'', and so rather confusingly the CTDSPL synonym is listed in the real "nif" gene record. And PMID 2307698 which talks about the unrelated "NIF-1" and "NIF-2" has crept into the "nif" record and I think it should be removed.


Overall, this confusion from the various uses of nif* - added to the fact that "NIF" is an alias for several mammalian genes - makes me think "nif" is not an ideal symbol. It seems only one group (BG Szaro) have published this ''Xenopus'' gene as '''NIF/XNIF/nif.'''
Overall, this confusion from the various uses of 'nif' - added to the fact that "NIF" is an alias for several mammalian genes - makes me think "nif" is not an ideal symbol. It seems only one group (BG Szaro) have published this ''Xenopus'' gene as '''NIF/XNIF/nif.'''


After some discussion , it was decided changes for the "nif"[XB-GENEPAGE-876556]   
After some discussion , it was decided changes for the "nif" [XB-GENEPAGE-876556]  genes  at Xenbase and Zfin as follows:


SYMBOL: NEFF1 (found in Xenopus)  
SYMBOL: NEFF1 (found in Xenopus)  
NAME: neuronal intermediate filament family member 1
NAME: neuronal intermediate filament family member 1
ALIAS: nif, Xnif
ALIAS: nif


and "NEFLL" genes:
and "NEFLL" genes:
SYMBOL: NEFF2 ( LOST IN FROGS)
SYMBOL: NEFF2 (LOST IN FROGS)
NAME: neuronal intermediate filament family member 2
NAME: neuronal intermediate filament family member 2
ALIAS:
ALIAS:

Revision as of 07:46, 5 May 2023

neff1

This is the community wiki page for the gene neff1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


background to nomenclature changes

05May2023

NCBI refSeq and HGNC communicated the following....

...there seems to be some confusion in the Xenbase "nif" record XB-GENEPAGE-876556: there is an unrelated gene that has also been published as "XNIF" (PMID 15294863/AY280863) which from BLATing the sequence maps to chr 6 and appears to be ctdspl, and so rather confusingly the CTDSPL synonym is listed in the real "nif" gene record. And PMID 2307698 which talks about the unrelated "NIF-1" and "NIF-2" has crept into the "nif" record and I think it should be removed.

Overall, this confusion from the various uses of 'nif' - added to the fact that "NIF" is an alias for several mammalian genes - makes me think "nif" is not an ideal symbol. It seems only one group (BG Szaro) have published this Xenopus gene as NIF/XNIF/nif.

After some discussion , it was decided changes for the "nif" [XB-GENEPAGE-876556] genes at Xenbase and Zfin as follows:

SYMBOL: NEFF1 (found in Xenopus) NAME: neuronal intermediate filament family member 1 ALIAS: nif

and "NEFLL" genes: SYMBOL: NEFF2 (LOST IN FROGS) NAME: neuronal intermediate filament family member 2 ALIAS:


Xenbase actions: 1) removed 2 synonyms (Xnif and CTDSPL) from the "nif " gene page [XB-GENEPAGE-876556]

2) updated nomenclature to neff1, neuronal intermediate filament family member 1, with synonyms: nif