XB-FEAT-877238: Difference between revisions

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=loc100491166=  
=''gdpd4''=  
This is the community wiki page for the gene ''loc100491166'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
This is the community wiki page for the gene ''gdpd4'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase


=Nomenclature changes=
=Nomenclature changes=
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Added to gene function: "such as GDPD5 are involved in glycerol metabolism." based on description supplied by OMIM [Jan 2010]".
Added to gene function: "such as GDPD5 are involved in glycerol metabolism." based on description supplied by OMIM [Jan 2010]".
 
=Summary for human GDPD5 from NCBI=
 
17AUG2022
22MAY2023
   
 
Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]
Based on synteny with human, it is clear that this gene was misidentified (albeir provisonally) and is actually the ortholog of GDPD4 (not GDPD5).
 
''Xenopus'' gene name change from 'provisional ortholog of glycerophosphodiester phosphodiesterase domain containing 5' to 'glycerophosphodiester phosphodiesterase domain containing 4'
 
''Xenopus'' gene symbol changed from ''XB877238 [provisional:gdpd5]'' to ''gdpd4''
 
 
=synteny and orthology=
 
SYnteny is conserved between frogs and human, and confirms that this gene is the true orthology of human GDPD4.
 
''X. tropicalis'' Chr2: ''aqp11<  pak1>  '''gdpd4'''>  muyo7a<''
 
Human:  AQP11< PAK1> '''GDPD4'''> MYO7A<

Latest revision as of 09:12, 22 May 2023

gdpd4

This is the community wiki page for the gene gdpd4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

Nomenclature changes

17AUG2022

Gene symbol changed from "XB877238 [provisional:gdpd5]" to "gdpd5 (provisional)".

"XB877238" added as a gene synonym.

Gene name changed from "provisional ortholog of glycerophosphodiester phosphodiesterase domain containing 5" to "glycerophosphodiester phosphodiesterase domain containing 5 (provisional)".

Added to gene function: "such as GDPD5 are involved in glycerol metabolism." based on description supplied by OMIM [Jan 2010]".


22MAY2023

Based on synteny with human, it is clear that this gene was misidentified (albeir provisonally) and is actually the ortholog of GDPD4 (not GDPD5).

Xenopus gene name change from 'provisional ortholog of glycerophosphodiester phosphodiesterase domain containing 5' to 'glycerophosphodiester phosphodiesterase domain containing 4'

Xenopus gene symbol changed from XB877238 [provisional:gdpd5] to gdpd4


synteny and orthology

SYnteny is conserved between frogs and human, and confirms that this gene is the true orthology of human GDPD4.

X. tropicalis Chr2: aqp11< pak1> gdpd4> muyo7a<

Human: AQP11< PAK1> GDPD4> MYO7A<