XB-FEAT-972563: Difference between revisions
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=fto= | =fto= | ||
This is the community wiki page for the gene ''fto'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''fto'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=Summary from NCBI for human FTO= | |||
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011] | |||
=nomenclature changes= | |||
updated change. | |||
Human name has changed for Entrez Gene: 79068. From fat mass and obesity associated to FTO, alpha-ketoglutarate dependent dioxygenase | |||
05.13.19 | |||
Human name has changed for Entrez Gene: 79068. From FTO, alpha-ketoglutarate dependent dioxygenase to FTO alpha-ketoglutarate dependent dioxygenase | |||
Latest revision as of 09:07, 15 May 2019
fto
This is the community wiki page for the gene fto please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
Summary from NCBI for human FTO
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
nomenclature changes
updated change.
Human name has changed for Entrez Gene: 79068. From fat mass and obesity associated to FTO, alpha-ketoglutarate dependent dioxygenase
05.13.19
Human name has changed for Entrez Gene: 79068. From FTO, alpha-ketoglutarate dependent dioxygenase to FTO alpha-ketoglutarate dependent dioxygenase