Colcemide: Difference between revisions

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(Created page with "Molecular probes http://www.xenbase.org/literature/article.do?method=display&articleId=11687")
 
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Molecular probes
==Description==
synonym: Demecolcine
"Demecolcine is a colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division."
*-Pubchem Description


http://www.xenbase.org/literature/article.do?method=display&articleId=11687
[[File:colcemide.png|frame|right|Colcemide structure, photo from PubChem]]
 
==Genes Affected==
 
==Suppliers==
*[http://www.xenbase.org/entry/ Molecular Probes]
 
==Usage Notes==
 
==References==
*[https://pubchem.ncbi.nlm.nih.gov/compound/220401 Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=11687 Lautermilch et al., 2000]
 
>143 Xenbase articles contain a reference to colcemid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Revision as of 09:40, 13 October 2015

Description

synonym: Demecolcine "Demecolcine is a colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division."

  • -Pubchem Description
Colcemide structure, photo from PubChem

Genes Affected

Suppliers

Usage Notes

References

>143 Xenbase articles contain a reference to colcemid according to textpresso